Syndrome Regularity Study On Preventing And Treating Cirrhosis Ascites Used By Men Jiuzhang Professor

Objective : Through observation and analysis of the outpatient medical record of Jiuzhang-Men in the treatment of hepatic fibrosis ascites by modern statistical methods,to obtain the formulate and syndrome rules of the treatment of hepatic fibrosis ascites,to summarize and analyze the characteristics of the formula syndrome and the inherent treatment thought,to explore the application of prescriptions,formulations and compatibility among the different groups in the treatment of the disease,in order to provide a new method for clinical treatment of this disease.Methods: To enter and review the data of 191 patients with hepatic fibrosis ascites who met the inclusion criteria.Establish a database by collecting the meterial such as general medical history,previous history,tongue pulse information and prescription information,Explore and analysis the internal relationships among prescription-symptom-medicine,formula-syndrome,prescription-prescription,With the means of frequency analysis,chi-square test,and clustering analysis to presented the results in the form of chart,and analyzes its intrinsic relationship.Results:The age distribution of hepatic fibrosis ascites was between 60 and 70 years old,with more males than females.The medical record involves more than 50 kinds of previous history,including 13 kinds of digestive system diseases,8 kinds of cancer and 8kinds of respiratory system diseases,which are widely distributed.Except for the direct relationship between hepatitis B and this disease,the history of diabetes is the most.In addition to the main symptoms related to hepatic fibrosis ascites(weakness,abdominal distension,appetite loss),poor sleep was the most common in concurrent symptoms,followed by constipation,bad mood,fear(evil)cold,irritability,cold hands and feet,emaciation,flank pain,cough and asthma,etc.The tongue pulse aspect by the tongue dark body fat,moss white,the pulse is heavy,the ruler pulse is fewer this disease core.Light red tongue,tongue body crack,thick moss,greasy moss,taut pulse,thready pulse is the next.In terms of syndrome types,spleen-kidney Yang deficiency is the core syndrome,followed by spleen-deficiency qi stagnation,liver-spleen disharmony,spleen-lung qi deficiency and spleen-deficiency water flooding.The core prescription for treating hepatic fibrosis ascites is xiangsha liujunzi decoction.According to the classification of prescriptions,the main prescription categories are divided into five categories,namely,xiangli invigorate spleenand dampness,wuling clearing damp and promoting diuresis,warming kidney-yang agent,bupleurum dredge and guide agent,and yi gong powder tonifying spleen and lung agent.The core prescription of invigorate spleen and dehumidifying is Xiangsha liujunzi decoction,The core prescription of clearing damp and promoting diuresis is Weiling decoction,The core prescription of warming kidney-yang is Fuzi decoction,The core of the prescription of bupleurum dredge and guide is Xiaoyao San;The core prescription in spleen-lung prescriptions is Yigong San.The combination forms of consortium group mainly include unilateral,two-party combination,three-party combination and four-party combination.Two-party combination is the core combination form,followed by three-party combination.There are 20 specific combinations of the joint group,among which the single group,Xiangsha liujunzi decoction is the core,and the combination of xiangli and ling in the joint group is the core combination.The commonly used combination groups are: xiangli·ling·fu combination,xiangli·fu combination,xiangli·chai combination,xiangli·ling·chai combination,fu·ling combination,yigong·fu combination,yigong·chai combination,fu·chai combination,chai·ling combination,etc.According to the clustering results of symptoms and the consortium group,they are mainly divided into 8categories.The first category: Xiangli class and Fuzi class,Chaihu class,Yigong class,Xiangli·fu combination,Xiangli·ling·fu combination,Xiangli·ling combination,Xiangli·chai combination,Yigong·fu combination,Chai·ling combination;The second kind: Fu·ling combination,Fu·chai combination,Xiangli-yigong combination;The third type: Yigong·chai combination,Yigong·ling·fu combination;The fourth category:Yigong·fu combination;The fifth kind: ling·fu·chai combination;The sixth category:ling·fu·chai combination;Category 7: Fu·chai combination;Category 8: Yigong·fu combination,Xiangli·ling· chai combination.There are 43 kinds of drugs in addition and substraction,the core of which is Zhishi(Aurantii fructus immaturus),followed by Huai-niuxi(Achyranthis bidentatae radix),Cheqianzi(Plantaginis smen),Zisuzi(Perilae fructus),Kuandonghua(Farfarae flos),Qianshi(Eryales semen),and Yinchen(Artemisae scopariae herba).It is conclude that clustering analysis result in six kinds of plus and minus compatibility,The first category: Cheqianzi(Plantaginis smen),Zhishi(Aurantii fructus immaturus);The second kind: Huainiuxi(Achyranthis bidentatae radix);The third category:Wuweizi(Schisandrae chinensis fructus);The fourth category: Danpi(Moutan cortex),Yuanzhi(Polygalae radix);The fifth Category : Yinchen(Artemisae scopariae herba).The sixth type: Su zi(Perilae fructus),Kuandonghua(Farfarae flos),Qianshi(Eryales semen).Conclusion:Hepatic fibrosis ascites,which is a difficult disease,When considering treatment principles,personal factors such as gender,age,previous history and living habits should be taken into account,Syndrome and cause should be treated together,The major and fundamental contradictions of the patients were comprehensively analyzed so as to select more appropriate formulas and combinations for intervention.It focuses on the overall functional state of the human body shown by the relationship between the tongue pulse,and reflects the relationship between evil and positive through the tongue pulse,so as to establish the overall direction of treatment.The tongue is dark,fat and mote white,the pulse is heavy,and the chord is thin,which serves as the core tongue pulse of hepatic fibrosis ascites and provides reliable evidence for guiding treatment.In terms of treatment,the combination factors of the basic prescriptions are mainly xiangli tonifying spleen and dehumidification,wuling clearing damp and promoting diuresis,warming kidney-yang agent,bupleurum dredge and guide agent,and yi gong powder tonifying spleen and lung agent.In the treatment of the disease,the combination of the four diagnostic information and the overall judgment of the body is used,with the combination group as the main and the single prescription as the auxiliary,Among them,single Xiangsha liujunzi decoction is the core,and the joint group is the core of two parties,and its core combination is:Xiangli·ling combination;The core of tripartite association as the main auxiliary is:Xiangli·ling·fu combination.There were a total of 20 combinations in the treatment,which were statistically significant by Fisher's exact test,and there was a certain internal relationship between the combination group.In the treatment of the main aspects are:Soothing liver and activating spleen,xingyang temperature transport,double tonifying spleen lung,protecting the stomach qi,Syndrome and cause are treated together strengthening vital to eliminate pathogenic factor,the use of the combination of the group is mainly reflected in: small prescription,different weight,overall consideration.The core of addition and subtraction drugs was Zhishi(Aurantii fructus immaturus),and the clustering results were the first class of Zhishi(Aurantii fructus immaturus)and Cheqianzi(Plantaginis smen),which reflected the principle of promoting the circulation of Qi and dehumidification.Adjuvant drugs include Huainiuxi(Achyranthis bidentatae radix)type and Wuweizi(Schisandrae chinensis fructus)categories,reflecting the principle of promoting blood circulation and nourishing Yin;Danpi(Moutan cortex),Yuanzhi(Polygalae radix)class,reflecting the principle of clearing deficient heat and Calming nerves god;Yinchen(Artemisae scopariae herba)type,reflecting the principle of dampexcreting anti-icteric;Su zi(Perilae fructus),Kuandonghua(Farfarae flos),Qianshi(Eryales semen),reflects the principle of invigorating lung and kidney.