Clinical Studies On Brain Injury Complicated With Hyponatremia

Objective: We discuss the incidence of hyponatremia,the independent risk factors and prognosis,etc.through the study on the occurrence of hyponatremia in patients with traumatic brain injury and help to the clinical work in prevention and treatment.Methods: Patients admitted to hospital during January 1,2017 to December 31,2017 were selected to be subjects,all of them were hospitalized for more than 72 hours and definitively examined with TBI by imaging and clinical diagnosis.The patients were divided into two groups: normal sodium and sodium hyponatremia,according to the ion monitoring on them.The general condition,degree of injury(GCS score),different types of injury and the relation between the presence of different complications and hyponatremia were analyzed.Results: 1.A total of 218 patients were selected in the study criteria,104 of which were found with hyponatremia,and the total incidence rate is 47.71%(104/218).2.Traumatic subarachnoid hemorrhage,acute epidural hematoma,intracerebral hematoma,diffuse axonal injury,cerebrospinal fluid leakage,stress gastrointestinal bleeding and hyperthermia are statistically significant in the occurrence of hyponatremia(P <0.05).3.t SAH,intracerebral hematoma,cerebrospinal fluid leakage,moderate and severe injury,high fever and stress gastrointestinal bleeding are the independent risk factors in the occurrence of hyponatremia.(P<0.05).4.Patients with moderate or severe traumatic brain injury who were found with hyponatremia had a longer hospital stay and a poor prognosis(P<0.05).5.The occurrence of hyponatremia in the patients with moderate or severe traumatic brain injury mostly was focused in the first two weeks from hospitalization,especially the second week.Conclusion: 1.Patients with traumatic brain injury are prone to hyponatremia during treatment,and the incidence rate is 47.71%.2.The low sodium condition occurred in the patients with moderate or severe traumatic brain injury mainly was focused in the first two weeks after the injury,especially the second week.3.t SAH,brain contusion,cerebrospinal fluid leakage,GCS score <12,high fever,stress gastrointestinal bleeding are the independent risk factors in the occurrence of hyponatremia.4.Hyponatremia has a significant adverse impact on the patients with traumatic brain injury in the period of hospital stay and the prognosis.