Risk Factors Analysis For Reversible Ischemic Neurologic Deficit After Revascularization In Patients With Moyamoya Disease

OBJECTIVEThis study was designed to identify the risk factors and independent risk factors of Reversible Ischemic Neurologic Deficit after Revascularization in the patients with Moyamoya Disease.METHODS233 cases of moyamoya disease admitted to the First Affiliated Hospital of Zhengzhou University from January 1,2016 to June 30,2018 were preliminarily screened.According to the selection and exclusion criteria,152 patients met the inclusion criteria.In this study,single factor analysis and other statistical methods were used to analyze the risk factors of RIND after MMD,and logistic regression analysis was used to identify the independent risk factors of complications after MMD.RESULTSA total of 180 revascularization operations were performed in 152 patients,RIND occurred in 30 cases(30/180,with a probability of 16.67%).Univariate statistics showed that preoperative bilateral cerebral perfusion insufficiency,preoperative stroke history,severe hypertension(hypertension grade II-III),higher Rankin score and multiple morbidity were risk factors for postoperative RIND(P < 0.05).Clinical manifestations,gender,age,bell were risk factors for postoperative RIND.There was no significant correlation between RIND and Suzuki level,number of operations,history of diabetes mellitus,drinking history,operation time and smoking history(P > 0.05).Logistic regression analysis showed that preoperative bilateral cerebral infusion insufficiency,Rankin score >2,hypertension and multiple onsets were independent risk factors for RIND.CONCLUSIONPreoperative brain perfusion insufficiency and neurological function loss are widespread,clinical symptoms are frequent,and patients with more severe hypertension,hyperlipidemia and other chronic diseases are more likely to develop RIND after surgery.