Correlation Between Obstructive Sleep Apnea Hypopnea Syndrome And NLR

ObjectiveTo explore the correlation between obstructive sleep apnea hypopnea syndr ome(OSAHS)and NLRMethods130 cases of OSAHS patients with polysomnography(PSG)and blood routine examination on 27 healthy volunteers were height,weight and blood routine examination,sleep monitoring.Sleep monitoring key indicators include:body mass index(BMI),apnea index(AI),apnea-hypopnea index(HI),sleep apnea hypoventilation index(AHI),the lowest oxygen saturation(LSa02),and the average blood oxygen saturation(MSa02).Blood routine surveillance main indicators include:white blood cell count(WBC),red blood cell count(RBC),Neutrophil count,Neutrophil,lymphocyte count(LYM),platelet count(PLT),Neutrophil/lymphocyte ratio(NLR),the standard deviation of red blood cell distribution width(RDW-SD)and coefficient of variation of red blood cell distribution width(RDW-CV),platelet distribution width(PDW).According to the value of sleep monitoring results of AHI OSAHS group can be divided into mild group,moderate group,severe group.Comparison between groups of BMI,AI,HI,AHI,MSa02,LSa02 index and the correlation of NLR,and compare the NLR difference between experimental group and control group,and the experimental group in the light,medium and heavy NLR difference between the three groups.Results1.In severe OSAHS group NLR can predict the severity of the disease,the difference was statistically significant(P=0.001),mild OSAHS group and moderate OSAHS group NLR can't predict the severity of the disease,there was no statistically significant difference(P>0.05);2.In OSAHS group,NLR and HI,AHI and AI were significantly positive correlation,but in NLR and RDW-SD,RDW-CV,PDW minimum average blood oxygen saturation and blood oxygen saturation and other indexes had no significant correlation;3.Mild OSAHS group,the moderate OSAHS group and the severe OSAHS group each group of NLR,AHI,AI,and HI RDW SD,RDW CV and other indexes had no significant correlation;Conclusion1.OSAHS patients with disease progression,peripheral blood NLR has significantly upward trend,NLR can be used to predict the severity of the disease severe OSAHS patients.2.OSAHS patients with changes in peripheral blood of NLR and intermittent hypoxia at night and the severity of sleep apnea were positively correlated,index can be used as auxiliary diagnosis of OSAHS.