| Objectives Polycystic ovary syndrome(PCOS)is one of the main causes of anovulatory infertility in women of childbearing age[1].In this study,the ovulation of patients with polycystic ovary syndrome(PCOS)was induced by oral administration of traditional Chinese medicine decoction,acupoint acupuncture of traditional Chinese medicine,combination of traditional Chinese medicine and acupuncture and intramuscular injection of Western medicine HCG.The clinical efficacy of the four treatment methods was observed and compared.The characteristics and advantages of traditional Chinese medicine in treating ovulation disorder infertility of PCOS were expounded,which provided the basis for the treatment of this disease by traditional Chinese medicine.Methods:Observed and analyzed 120 cases of ovulation disorder infertility of polycystic ovary syndrome,divided into four groups according to the treatment plan,each group of 30 patients,To observe the ovulation,clinical pregnancy,progesterone,LUFS and OHSS in four groups.Results:(1)Ovulation:117 cycles were treated in the Chinese medicine group,the ovulation rate was 52.99%;101 cycles in the acupuncture group,the ovulation rate was 58.42%;103 cycles in the acupuncture and medicine group,the ovulation rate was 72.82%;120 cycles in the western medicine group,the ovulation rate was 55.00%.The ovulation rate of the acupuncture group was significantly higher than that of the traditional Chinese medicine group,the acupuncture group and the western medicine group(P<0.05).(2)Levels of serum estrogen and progesterone in the middle luteal phase:Statistical analysis of serum estrogen and progesterone levels in four groups in the middle luteal phase:group A,E2:215.17±136.42pg/mL,P:11.82±10.21ng/mL;group B,E2:268.47±164.11pg/mL,P:16.05 + 13.19 ng/mL;group C,E2:340.74 + 165.51 pg/mL,P:22.16+14.88 ng/mL;group D,E2:269.58+161.70 pg/mL,P:14.73+13.20 ng/mL.The serum E2 value of mid-luteal phase in western medicine group was higher than that in traditional Chinese medicine group and lower than that in acupuncture group,with statistical significance(P<0.05).The serum E2 value of mid-luteal phase in western medicine group was higher than that in acupuncture group,with no statistical significance(P>0.05).The serum P value of mid-luteal phase in western medicine group was higher than that in traditional Chinese medicine group and lower than that in acupuncture group,with statistical significance(P<0.05).The serum P value of mid-luteal phase in western medicine group was lower than that in acupuncture group,with no statistical significance(P>0.05).(3)Clinical pregnancy comparison:Group A 30 cases,clinical pregnancy 10 cases,clinical pregnancy rate 33.33%;Group B 30 cases,clinical pregnancy 12 cases,clinical pregnancy rate 40.00%;Group C 30 cases,clinical pregnancy 14 cases,clinical pregnancy rate 46.67%;Group D 30 cases,CL 11 cases.The clinical pregnancy rate was 36.67%.The clinical pregnancy rate of group B and group C was higher than that of group D.The clinical pregnancy rate of group C was the highest,but there was no significant difference between the two groups(P>0.05).(4)Comparisons of complications:117 observation cycles in group A,15 cycles in LUFS(12.82%)and 0 cycles in OHSS(0%);101 observation cycles in group B,12 cycles in LUFS(11.88%)and 0 cycles in OHSS(0%);103 observation cycles in group C,12 cycles in LUFS(11.65%)and 12 cycles in OHSS(0%);120 observation cycles in group D,respectively.LUFS occurred in 29 cycles(24.17%)and mild OHSS occurred in 8 cycles(6.67%).The incidence of LUFS was lower in group A,group B and group C than in group D(P<0.05),and the incidence of OHSS was lower in group A,group B and group C than in group D(P<0.05).Conclusion:The use of different TCM techniques in the treatment of polycystic ovary syndrome ovulation disorder infertility can improve the cycle ovulation rate,clinical pregnancy rate,reduce the incidence of LUFSS and OHSS,Among them,the combination of acupuncture and medicine has the best curative effect.TCM treatment has safety and effectiveness. |
