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Analysis Of The Correlation Between Different Types Of Gangrene Of Digit And TCM Physica

Posted on:2020-10-15Degree:MasterType:Thesis
Country:ChinaCandidate:X L OuFull Text:PDF
GTID:2404330572976160Subject:Chinese traditional surgery
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Objective: To study the type "Gangrene of Digit" syndrome differentiation of traditional Chinese medicine and traditional Chinese medicine physique,ankle brachial ankle index(ABI),arm pulse wave conduction velocity(Bapwv),general observation index(gender,age,BMI)and the correlation between laboratory examination indexes(four,hemorrheology indexes,uric acid,blood lipids homocysteine)difference or relevance,thus for clinical diagnosis and treatment of traditional Chinese medicine has a certain guiding significance to improve clinicians combine traditional Chinese and western medicine diagnosis and treatment level.Methods: the cases in this study were from the outpatient and inpatient patients of peripheral vascular surgery department of our hospital from January 2018 to March 2019.33 cases met the inclusion criteria,ranging from 21 to 89 years old,including 20 male patients and 13 female patients.Through statistical analysis,the TCM syndromes and physical conditions of the patients with apostosis were analyzed,and the TCM syndromes and physical conditions,ABI,Bapwv and related observation indexes were discussed.Results:1.A total of 33 cases of "Gangrene of Digit" patients were included in this study,which were divided into five main syndrome groups according to syndrome differentiation,including 10 cases of cold and dampness,7cases of blood stasis,6 cases of qi and blood deficiency,6 cases of stagnation and toxin decay,and 4 cases of dampness and heat.2.There was no statistically significant difference in the unilateral lowest ABI between the five main syndromes groups(P > 0.05).The difference of average Bapwv between five groups was statistically significant(P <0.05).The pawn comparison of average bapwv value among the five groups showed that there was a statistically significant difference between the two groups(P = 0.035),and the rank mean of the two groups was lower than that of the two groups,while there was no significant difference between the other groups.3.Thirty-three cases of apostosis were classified as sclerotic group according to Bapwv mean 1400cm/s and non-sclerotic group according to Bapwv mean 1400cm/s,to explore the correlation between arteriosclerosis and the five main syndromes.Bapwv mean grouping in the study subject cannot be considered to be related to the main syndrome(P > 0.05).4.Among the subjects,the five main syndromes had nothing to do with gender(P > 0.05).The patients with apostosis were divided into two groups,and the average Bapwv and ABI of the two groups werecompared.There was no significant difference in ABI between the two groups(P > 0.05).5.The correlation between average Bapwv and ABI in apostolic patients and all indexes: statistical analysis showed that there was a positive correlation between uric acid and average Bapwv(r = 0.492,P =0.004).Age was positively correlated with mean Bapwv(r = 0.671,P <0.01).Homocysteine was positively correlated with mean Bapwv(r = 0.39,P = 0.025).There was a negative correlation between hematocrit and mean Bapwv(r =-0.438,P < 0.01).There was a positive correlation between the unilateral lowest ABI and the related observational indexes in the patients with apostosis: age was positively correlated with the unilateral lowest ABI(r = 0.163,P = 0.014).6.Observation of blood lipid correlation and comparison of BMI indexes between the five main syndromes groups: statistical analysis indicated that there were no statistically significant differences in blood lipid correlation and BMI between the five main syndromes groups(P >0.05).Patients with BMI < 24 were assigned a value of 0,24 BMI < 27 were assigned a value of 1,and patients with BMI > 27 were assigned a value of 2.After statistical analysis,it could not be considered that there was a correlation between BMI grouping and principal evidence in the study subjects(P > 0.05).7.Comparison of hemorheology related observation indexes between thefive main syndromes groups: statistical analysis indicated that there were no statistically significant differences in blood lipid related observation indexes and BMI between the five main syndromes groups(P > 0.05).8.Comparison of serum uric acid and homocysteine between the five main syndromes groups: statistical analysis indicated that there were no statistically significant differences in serum uric acid and homocysteine between the five main syndromes groups(P > 0.05).9.Comparison between TCM constitution and main diseases of Gangrene of Digit: according to statistical analysis,it cannot be considered that there is a correlation between five main diseases of Gangrene of Digit in TCM constitution types(P > 0.05).Conclusion: 1.In the classification of the main syndromes of "desensification" in traditional Chinese medicine,the lowest ABI on one side can be used as one of the objective indexes for the differentiation of the main syndromes of cold and dampness,blood stasis and other main syndromes,but it needs to be further confirmed.2.In TCM "decoloration" syndrome differentiation,the five main syndromes are not strictly closely related to the degree of lower limb ischemia.As the disease turns,the degree of lower limb ischemia improves,and the unilateral lowest ABI tends to increase.3.In this study,a positive correlation was observed between ABI and age,but further verification is needed.4.Among the patients with arteriosclerosis obliterans of lower limbs diagnosed as "Gangrene of Digit" in traditional Chinese medicine,Bapwv value may be one of the objective indexes of syndrome differentiation of stagnation and toxin decay and cold and dampness.5.People with TCM constitution of qi deficiency may be more prone to "Gangrene of Digit" than those with other constitutions.In this study,it was found that Bapwv was positively correlated with age,erythrocyte sedimentation rate and homocysteine in the patients diagnosed with "Gangrene of Digit",but it still needs to be further confirmed.
Keywords/Search Tags:Gangrene of Digit, TCM constitution, TCM syndrome differentiation, brachial-ankle index, brachial-ankle pulse wave velocity
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