Analysis Of Risk Factors Of Venous Thromboembolism After Craniocerebral Trauma Score Based On Caprini

Objective: To verify the validity of Caprini Thromboembolism Risk Assessment Scale in predicting venous thromboembolism after craniocerebral trauma,and to analyze the risk factors according to the clinical characteristics of patients with craniocerebral trauma,so as to provide reference for the prevention,intervention and diagnosis of clinical VTE.Methods: A retrospective case-control study was conducted to collect 27 VTE patients admitted to the Neurosurgery Center of the First Affiliated Hospital of Xinjiang Medical University from January 2013 to June 2018 as case group.54 VTE-free patients admitted to the hospital at the same time were randomly selected as control group.The two groups were assessed by Caprini risk score and risk grading.The risk factors of VTE were analyzed by multivariate logistic regression according to the characteristics of patients with craniocerebral trauma.Results:(1)There were significant differences in age,open craniocerebral injury,paralysis,GCS score and intraoperative blood transfusion between VTE group and control group(P < 0.05).Further multivariate logistic regression analysis showed that intraoperative blood transfusion(OR = 4.445,95% CI: 1.105-17.880,P =0.036),open craniocerebral injury(OR = 5.284,95% CI: 1.455-19.193,P = 0.011)were independent risk factors for VTE after craniocerebral trauma.The regression equation is Logit(P)=-1.406+1.492X1+1.665X2.(2)Caprini score in VTE group was significantly higher than that in control group,with difference(P < 0.001);the composition of risk grading in case group and control group was different(P < 0.001).In VTE group,the proportion of high-risk patients was 93%.In control group,the proportion of middle-risk patients was the most(37%)followed by high-risk patients(31%).Conclusions: Caprini Thromboembolism Risk Assessment Scale can better predict the risk of venous thromboembolism after craniocerebral trauma;For patients with open craniocerebral injury and intraoperative blood transfusion,it is necessary to actively prevent andintervene in VTE.