The Clinical Study On CT-Guided Argon-Helium Cryoablation For Soft Tissue Sarcomas

Objective:To evaluate the ablation rate and complications of 60 patients with soft tissue sarcomas who had been treated by argon-helium cryoablation and to investigate the effectiveness and safety of argon-helium cryoablation in the treatment of soft tissue sarcomas.To analyze the influencing factors of the ablation rate after cryoablation treatment of soft tissue sarcomas.Methods:Using retrospective research method,60 patients with soft tissue sarcomas who underwent argon-helium cryoablation treatment during May 2011 and October 2017 were selected.After argon-helium cryoablation treatment for 1 month,CT or MRI examination was performed to assess the ablation rate.The statistical analysis was conducted to observe the influencing factors on the ablation rate of argon-helium cryoablation treatment.The complications related with argon-helium cryoablation were summarized,and the severity of complications was assessed according to the complication grading criteria of Society of Interventional Radiology.Results:Cryoablation was successfully performed on 60 patients,and no cases of terminated cryoablation were seen due to pain and other reasons.Varying degrees complications related to argon-helium cryoablation had occurred in 31 patients,with the total incidence of complications being 51.67%,the complication grading criteria of Society of Interventional Radiology were either A or B.No severe infection,skin necrosis,bleeding,organ dysfunction and shock had occurred in cryoablation.The average ablation rate after cryoablation of 60 soft tissue sarcomas was(83.02 ± 17.07)%.The univariate analysis showed that the largest diameter of tumor and tumor location were related to the ablation rate after cryoablation(?2= 10.408,P=0.015;?2=36.778,P=0.006),while the multivariate analysis showed that tumor location was the independent influencing factor on ablation rate of cryoablation treatment for soft tissue sarcomas(P<0.05).Conclusion:CT-guided argon-helium cryoablation is safe and effective in the treatment of soft tissue sarcomas.Tumor location is an independent influencing factor on the ablation rate of argon-helium cryoablation for soft tissue sarcomas.