Related Factors Of Lower Cranial Nerves Injury In Large Acoustic Neuroma Surgery

Objective The aim of this study was to report the postoperative lower cranial nerves(LCNs)function in patients undergoing surgery for large acoustic neuroma(LAN)and to evaluate risk factors for postoperative LCNs dysfunction.Methods From January2015 to September2018,106 Large acoustic neuromas(LAN)microsurgically removed via retrosigmoid transmeatus approach,all used continuous electrophysiological monitoring in operation,were retrospectively analyzed.According to the standard and LCNs function106 patients involved were assigned into LCNs injury group(9 cases),and the rest patients were assigned into non-injury group(97 cases),clinical date were collected and comparative analysis of age,sex,tumor size,courses of disease,solid or cystic,whether the hydrocephalus,adhesion with brainstem,duration of surgery,amount of bleeding,total or subtotal resection and other factors,retrospectively analysis of LCNs injured patients after microsurgery related factors.Results Multivariate Logistic regression analysis was performed for all factors considered,the tumor size(OR 19.758,95%CI1.812~19.941;P=0.002),the preoperative hydrocephalus(OR 12.537,95%CI 1.546~89.109;P=0.025)and adhesion with brainstem(OR 2.536,95%CI 1.798 ~ 16.196;P=0.041)were statistically significant.Conclusion There are many factors affecting the LCNs function in LAN surgery.The related factors in this study include: the tumor size,the preoperative hydrocephalus and adhesion with brainstem.