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Study On TCM Constitution Distribution And Related Factors In Patients With Hypertension Based On Regression Analysis

Posted on:2020-09-11Degree:MasterType:Thesis
Country:ChinaCandidate:Y H LiFull Text:PDF
GTID:2404330572481567Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Objective:To investigate the distribution of TCM constitution types and related factors with hypertension in patients with hypertension,and to provide new ideas for interfering with the disease from the perspective of physical constitution,so as to improve the clinical diagnosis and treatment of TCM.Methods : From the Ruikang Hospital affiliated to Guangxi University of Traditional Chinese Medicine,the Donglong Center Health Center of the Qiangtang District of Guigang City,and the Daling Center Health Center,1314 people were selected as the research subjects,and1042 cases of hypertension in the case group and 272 cases of normal people in the control group were performed.Questionnaire.According to the "Chinese Medicine Constitution Classification and Judging Criteria" promulgated by the Chinese Medicine Association in 2009,the relevant subjects were identified.At the same time,the basic conditions of the subjects(gender,age,height,weight,body mass index,waist circumference,hip circumference,blood pressure level,heart rate,smoking history,drinking history,family history,tongue pulse)and biochemical tests(uric acid,creatinine,serum)were collected.Total cholesterol,triglycerides,high-density lipoprotein,low-density lipoprotein,fasting blood glucose).SPSS22.0 software was used for 2tests,logistic regression analysis and other statistical analysis to study the distribution of TCM constitution types in hypertension patients and the correlation with related factors.Results:(1)The composition of TCM constitution of hypertension patients is mainly biased,among which phlegm-dampness(29.30%),yin deficiency(26.10%),yang deficiency(18.10%),and damp-heat(12.50%)are the most common.These four biased constitutions accounted for86.00%,and the proportion of peace and quality was small,accounting for 3.40% of the case group.In the normal population,the composition ratio of TCM constitution is the highest,accounting for 54.40%.Case group and control group were tested by 2,(49)<0.05,and the difference in body composition between the two groups was statistically significant.(2)When the high blood pressure group is divided by sex,the male hypertensive patients are mostly phlegm-dampness,accounting for32.60% of the total number,and the remaining 8 constitutions account for67.40%.Among women with hypertension,the proportion of Yin deficiency is higher,accounting for 27.60%,and other constitutions account for 72.40%.After 2 tests,there was no statistically significantdifference in the distribution of gender between the sexes,but there was a trend.In the control group,the physical and mental types of TCM were mostly in peace and quality,males accounted for 52.20%,and females accounted for 57.70%.There was no significant difference in the distribution of physical constitution between normal people.The distribution of gender between the control group and the case group was statistically significant.Among the hypertensive patients,the yin deficiency accounted for 58.30% before the age of 45,with a clear dominant position.With the increase of age,the biased constitution has gradually increased,with the highest age group of 60-75 years old.After60 years old,the proportion of phlegm-dampness was the highest,at29.50%,and the proportion of other biased physique was significantly lower than that of phlegm.There was a statistically significant difference in the distribution of TCM constitution types among patients with hypertension in different age groups.All age groups in the normal population are dominated by peace.The 45-59-year-old group and the60-75-year-old group were mainly phlegm-dampness,and the yin-deficiency type in the 60-75-year-old group increased compared with the <45-year-old group and the 45-59-year-old group.There was no significant difference in the distribution of normal human body between different age groups.(3)The difference in the distribution of TCM constitution types in different body mass index was statisticallysignificant.Among them,obese people had more phlegm-dampness than other physiques;overweight patients had the most yin deficiency.There was no statistical difference in the distribution of body weight between different body mass indexes in the control group.The systolic blood pressure level of hypertensive patients was the highest in qi stagnation,followed by phlegm-dampness;the comparison between qi stagnation and qi dysfunction and yang dysfunction was significant difference;phlegm-dampness and qi-deficiency,The difference between yang deficiency,yin deficiency and damp heat was statistically significant.There was no significant difference in diastolic blood pressure between the various groups in the case group.There was no significant difference in heart rate between the various constitutions.In the control group,the systolic and diastolic blood pressures were the highest in qi deficiency and the heart rate was the highest in moist heat.There was no statistically significant difference between the three and the physique after one-way analysis of variance.(4)In terms of eating habits,the overall dietary preference was higher than that of the diet,while the proportion of the stagnation in the physique was the highest in the diet,which was 18.10%.Qi stagnation and phlegm-dampness lack of exercise accounted for a large proportion,accounting for 36.00% and 20.65% respectively.The smoking rate in phlegm-dampness is higher,and the quality is the second.The proportion of damp heat in drinking was the largest,at 34.61%.(5)Uric acid(UA),total cholesterol(TC),triglyceride(TG),high-density lipoprotein(HDL-C),and low-density lipoprotein(LDL-C)in eight major constitution types of hypertensive patients Compared with fasting blood glucose(FBG),the results showed that there were statistically significant differences in uric acid,total cholesterol,high-density lipoprotein,low-density lipoprotein,and fasting blood glucose levels among the eight constitutional types,while triglyceride levels were in the constitution.There is no significant difference between them.The uric acid level(381.49umol/L)was the highest in the phlegm-dampness group and the lowest in the qi-deficiency group(338.51umol/L).The level of total cholesterol in the sputum group(5.43mmol/L)was significantly higher than other body types.The average value of triglyceride in yang deficiency group was the highest(1.92mmol/L),and the content of triglyceride in qi stagnation group was the lowest(1.10mmol/L).There was no statistical difference between the groups.The highest level of high-density lipoprotein(1.88mmol/L)was in the qi-deficiency group,and the lowest was in the phlegm-dampness group(1.43mmol/L).The low-density lipoprotein level(2.86mmol/L)was the lowest in the peace group and the fasting blood glucose level in the Qi deficiency group(6.88mmol/L)was the highest.(6)Correlation analysis between physical fitness and various factors of the main Chinese medicine practitioners showed that the quality of the peace and the low density lipoprotein werenegatively correlated,and the qi deficiency was negatively correlated with exercise and total cholesterol.Yang deficiency is negatively correlated with total cholesterol and positively correlated with low density lipoprotein and age.Yin deficiency is negatively correlated with age and uric acid,and positively correlated with total cholesterol and exercise.The phlegm-dampness was positively correlated with hip circumference,total cholesterol and creatinine,and negatively correlated with high-density lipoprotein,exercise,and low-density lipoprotein.The damp heat quality was negatively correlated with total cholesterol and hip circumference,and positively correlated with low density lipoprotein and fasting blood glucose.There is a negative correlation between blood and low density lipoprotein.In the regression analysis of the related factors of qi stagnation and special sputum hypertensive patients,no independent variables entered the equation.Conclusions:(1)The physical fitness of patients with hypertension is mainly phlegm-dampness,yin deficiency and yang-deficiency,and its distribution is not related to gender,and is closely related to body mass index,blood pressure level,age and living habits.Normal body mass is dominated by peace.There was a statistically significant difference in the type of constitution between hypertensive and normal people.(2)Hypertensive uric acid has the highest uric acid level and total cholesterol content,and the highest level of high-density lipoprotein.The averagevalue of yang-deficient triglyceride was the highest,the level of low-density lipoprotein was the lowest,and the level of fasting blood glucose was the highest.(3)There is a certain correlation between peace and quality and low density lipoprotein.There is a certain correlation between qi deficiency and exercise and total cholesterol.There is a certain correlation between yang deficiency and blood lipids and age.Yin deficiency and age,uric acid Exercise,total cholesterol has a certain correlation,phlegm-dampness has a certain correlation with high-density lipoprotein,low-density lipoprotein,hip circumference,creatinine,exercise,moist heat and high-density lipoprotein,low-density lipoprotein,There is a certain correlation between hip circumference and fasting blood glucose.
Keywords/Search Tags:hypertension population, TCM constitution, distribution law, regression analysis, correlation
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