Clinical Features And Malignant Risk Factors Analysis Of Intraductal Papillary Mucinous Neoplasms Of The Pancreas

Objective: To explore the malignant risk factors of intraductal papillary mucinous tumors of the pancreas,and compare the sensitivity,specificity,positive predictive value,and negative predictive value of the European Evidence-based Guidelines and Fukuoka International Consensus in predicting malignant IPMN.Methods: The clinical and pathological features of 13 patients with IPMN were analyzed retrospectively.Results: Univariate analysis showed that the diameter of main pancreatic duct greater than or equal to 10 mm was a risk factor for malignant IPMN(P < 0.05),while gender,imaging classification,mural nodules,solid mass,abdominal pain,diarrhea,jaundice,weight loss,hypertension,diabetes,pancreatitis,tumor location,age,elevated CA199,elevated CEA,tumor diameter were not risk factors for malignant IPMN.The sensitivity,specificity,positive predictive value and negative predictive value were 100.0%(6/6),14.3%(1/7),50.0%(6/12)and 100.0%(1/1)for European Evidence-based Guidelines,and 83.3%(5/6),57.1%(4/7),62.5%(5/8)and 80.0%(4/5)for Fukuoka Consensus Standard.Conclusions: 1.The diameter of the main pancreatic duct(?10mm)is a malignant risk factor for IPMN.2.There was no significant difference in sensitivity and specificity between Euro-Evidence-Based Guidelines and Fukuoka International Consensus in predicting malignant IPMN.