Clinical Study On The Treatment Of Patients With Acute Cerebral Infarction By Acu Puncture Combined With Atenolol Thrombolysis

Objective: By observing NIHSS score,Hasegawa Intelligence Scale(HDS)score,Barthel Index,inflammatory factors and complications of patients with acute cerebral infarction,the efficacy and safety of Xingnao Kaiqiao acupuncture combined with ateplase thrombolysis in the treatment of acute cerebral infarction were evaluated.Methods: Sixty-four patients with acute ischemic stroke who were treated in the First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine from September 2016 to September 2018 were randomly divided into observation group and control group with 32 cases in each group.The control group was given ateplase for injection according to the guidelines,and then 45 mL was added to the body weight calculation,0.9 mg/kg body weight(maximum dose is 90 mg),10% of the total dose was first pushed intravenously,the remaining dose was intravenously dripped within 60 minutes,once a day,only once.In the observation group,on the basis of the treatment of the control group,the intervention of Xingnao Kaiqiao acupuncture was conducted once a day.Both groups were treated continuously for 4 weeks.The clinical effects of the two groups were observed,and the neurological impairment,cognitive function,assessment of daily living ability,related inflammatory factors and the occurrence of common complications were compared between the two groups.Results: Two groups of patients in NIHSS score,HDS score,Barthel index,inflammatory factors interleukin-6,IL-8,IL-12,IL-16 and tumor necrosis factor a,the number of patients with post-infarction hemorrhage,aspirationpneumonia,hypoproteinemia,the use of anti-anxiety drugs,the observation group was better than the control group(P < 0.05),the difference was statistically significant.Conclusion: Xingnao Kaiqiao acupuncture combined with ateplase has good clinical efficacy in treating acute cerebral infarction.It can improve the clinical symptoms of patients,improve the quality of life of patients,improve the level of inflammatory factors,reduce adverse reactions after infarction,and has good safety.