| Objective: Prostate cancer plays a very important role in urinary male reproductive system tumors.The number of patients with adenocarcinoma is also on the rise,and the growth rate is faster than in Europe and the United States.Multiple epidemics.Studies have shown that obesity is associated with increased risk and mortality in a variety of cancer types,including prostate cancer.The risk factors for the occurrence and progression of prostate cancer are still not very clear.The risk factors that have been identified are years.Age,ethnicity,genetics and other related factors.At present,the clinical evaluation of the index of the degree of malignancy of prostate cancer is clinically divided Period,serum PSA,Gleason score,in addition,there are still many factors,such as body mass index,blood lipids.The aim of this study was to investigate factors such as body mass index,blood lipids,lipoproteins,and pathology of patients undergoing prostate biopsy.The relationship between the malignancy of prostate cancer,to provide appropriate treatment for clinical prevention of prostate cancer and assessment of the malignancy of prostate cancer When it is based.Materials and Methods: The clinical data of patients with prostate cancer who underwent transrectal prostate puncture under the guidance of ultrasound in the First Affiliated Hospital of Dalian Medical University from January 2016 to September 2018 were retrospectively collected.According to the patient's blood PSA and Gleason.The scores were divided into high-risk prostate cancer and non-high-risk prostate cancer.Multivariate and bivariate logistic regression analysis were used to analyze the risk factors of high-risk prostate cancer.Spearman correlation analysis was used to analyze the correlation between Gleason score and body mass index and blood lipid in prostate cancer patients;P< 0.05 was statistically significant.Results: 1.A total of 53 patients with prostate cancer underwent ultrasound-guided transrectal prostate biopsy were enrolled in this study.According to the patient's Gleason score and PSA,the Gleason score of prostate cancer patients was ?8,and PSA?20 was divided into high-risk prostate.In the cancer group,the other groups were non-high-risk prostate cancer groups,including 24 patients in the high-risk group,accounting for 45.2%,and 29 patients in the non-high-risk group,accounting for 54.8%.The single factor comparison between the two groups showed statistically significant differences in body mass index(P<0.05),but there was no significant difference in age,blood glucose,blood lipids and lipoprotein between the two groups(P>0.05).Multivariate two-category logistic regression analysis showed that body mass index was a risk factor for prostate cancer as a high-risk prostate cancer.High-density lipoprotein was a protective factor for prostate cancer as a high-risk prostate cancer.Lipoprotein is not a risk of prostate cancer as a high-risk prostate cancer.factor.2.The Gleason score of prostate cancer patients was analyzed by Spearman correlation with age,body mass index,PSA,blood lipids,lipoprotein and other factors.The results showed that the body mass index of prostate cancer patients and the Gleason score of PSA and prostate cancer patients were positive.High-density lipoprotein was negatively correlated with Gleason score in patients with prostate cancer.There was no significant correlation between age,triglyceride,cholesterol,low-density lipoprotein and lipoprotein a in patients with prostate cancer and Gleason score(P>0.05).Conclusion: 1.Body mass index is a risk factor for prostate cancer as a high risk prostate cancer;high density lipoprotein is a protective factor for prostate cancer as a high risk prostate cancer.2.Body mass index,PSA was positively correlated with Gleason score in patients with prostate cancer;high-density lipoprotein was negatively correlated with Gleason score in patients with prostate cancer;age,triglyceride,cholesterol,low-density lipoprotein and lipoprotein and Gleason scores were not significant correlation. |
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