| 【 Objectives 】 By collecting 137 clinical cases of hospitalized patients with Type 2 diabetes(T2DM)and conducting the "Chinese medical body constitution(BC)classification and decision table" questionnaire survey,to analysis of correlation between BC of TCM in patients with T2 DM and chronic complications of T2 DM and clinical and biochemical indexes,to provide a theoretical basis for the prevention and treatment of chronic complications of T2 DM.【 Methods 】 Hospitalized patients were selected according to the criteria of diagnosis of T2 DM of the "Chinese constitution classification and decision table" field survey;Collecting the general data including gender,age and course of disease,family history,body height,body weight,hospital number,contact,and clinical biochemical indicators and auxiliary examination data;entering all the data in the EXCEL table,using SPSS 22 statistical analysis of the data.【Results】 1.137 cases of chronic complications in T2 DM patients,the frequency of distribution of TCM constitution(cases)from large to small in turn is:Qi deficiency 31(22.6%),Yin deficiency 26(19%),Yang deficiency19(13.9%)damp heat 16(11.7%),phlegm dampness 15(10.9%)and qi stagnation 13(9.5%),and gentleness 8(5.8%),blood stasis 5(3.6%),4(2.9%)special intrinsic quality.Because of the small number of patients with mild and qualitative blood stasis and special quality,it is impossible to conduct statistical analysis.Therefore,this study mainly discusses 6 constitutions: Qi deficiency,yin deficiency,Yang deficiency,damp heat,phlegm dampness and qi stagnation.2.The difference of age and sex in different constitutions has statistical significance.In this study,the 6 main constitutions age ranges from large to small: Yang deficiency,Qi deficiency,yin deficiency,qi stagnation,phlegm dampness,dampness and heat(P < 0.05);sputum,dampness and heat are mainly male,and qi depression is mainly female(P < 0.05).3.HDL-C at different levels in the constitutions from high to low is Qi stagnation> yin deficiency> Yang deficiency> qi deficiency >dampness phlegm >dampness;HDL-C in damp heat was lower than the level of Yang deficiency(P=0.012)and yin deficiency(P=0.039)and Qi Stagnation(P=0.024);HDL-C level in Qi stagnation was significantly higher than that of phlegm dampness(P=0.027).4.In 137 patients,the incidence of chronic complications ranged from large to small in order: DMM(122)(89.1%),>DPN(81,59.1%)>DR(64,46.7%)>DKN(48,35%).5.In the patients with damo heat,the incidence of T2 DM chronic complications from low to high is DKN=DPN < DR < DMM.6.The 3 chronic complications in yin deficiency,Yang deficiency,Qi deficiency and qi stagnation were more common.The chronic complications of phlegm dampness and damp heat were relatively single.【Conclusions】 1.The physique distribution of T2 DM patients with chronic complications accords with the evolution rule of diabetes pathogenesis,and is related to factors such as duration,age and sex.Damp heat,phlegm dampness and qi stagnation are the high risk constitution of diabetes at the early stage.Qi deficiency,Yang deficiency and yin deficiency are the main factors in later stage of diabetes.2.Humid heat,phlegm wet quality and Qi deficiency are the high risk physique of obesity.The proportion of overweight women with qi depression in climacteric is larger,and the level of HDL-C in damp heat and phlegm damp patients is relatively low.3.Constitution and chronic syndrome: The 4 chronic complications were followed by the incidence rate from large to small in order of diabetes related macroangiopathy >DPN>DR>DKN;Yin deficiency and yang deficiency are more likely to occur in DKN.The phlegm dampness quality is less DR and the incidence of DPN is lower;There are many kinds of complications in patients with Qi deficiency,yin deficiency and yang deficiency.The complications of damp heat,phlegm dampness and qi stagnation are relatively simple.The correlation between physical distribution and chronic complications may be related to course of disease,pathogenesis and viscera. |
PDF Full Text Request