Study On The Syndrome And Treatment Of Severe Mycoplasma Pneumoniae Pneumonia In Children

Objective:Based on a retrospective investigation and analysis of children with severe Mycoplasma pneumoniae pneumonia,we discussed the correlation between syndrome characteristics and clinical characteristics,so as to enhance awareness of severe mycoplasma pneumonia,improve the accuracy of diagnosis,and improve the level of diagnosis and treatment.Methods:161 cases of hospitalized cases in Shandong Provincial Traditional Chinese Medical Hospital from January 2015 to December 2017 were selected as the research subjects.The general situation,clinical symptoms,physical signs,laboratory examination and imaging examination were collected and collated by retrospective investigation.SPSS 17 software is used to establish a database for statistical analysis and processing.Results:Gender composition in this study,and the ratio between men and women had no significant difference(P>0.05);age,the prevalence of preschool children up to 96(59.6%)cases(P<0.05);the incidence season,northern autumn season incidence was significantly higher than that in spring and autumn(P<0.05);damp heat syndromes distribution.The number of cases closed the lung for a maximum of 77(47.8%)cases(P<0.05).Various types of gender distribution was not statistically significant(P>0.05);age distribution between the various syndromes,heat closed lungs and phlegm heat closed the lung were mainly in children aged 3~+-7(P<0.05);the seasonal distribution of various types,autumn and winter is the season of high incidence of severe MPP,damp heat of lung for more in the winter season(P<0.05).The children had multiple fever(P<0.05),and the proportion of the degree of fever in each type of syndrome was different(P<0.05).The pulmonary auscultation was not typical(100/161 cases,accounting for 62.1%),but there was no significant difference in the composition of respiratory sound among the various syndromes(P>0.05).The mean value of white blood cell count was 9.22±4.59×10~9/L,and the average count of white blood cells in each group was no difference(P>0.05).The mean value of C reactive protein count was 15.83±15.11mg/L,which was higher than that of normal value,but there was no difference in the count of C reaction protein(P>0.05).The average count of lactate dehydrogenase was 290.24±77.23U/L,which was higher than that of normal level,but the average count of lactate dehydrogenase in each type was no difference(P>0.05).There was no difference in the distribution of antibody titer of Mycoplasma in each type(P>0.05).Severe MPP was mainly associated with viral infection,and there was no significant difference in the distribution of pathogens among the various syndromes(P>0.05).In this group,lobar consolidation was the main type,accounting for 118/161(73.3%).There was a significant difference in the range of lesions(P<0.05),but there was no significant difference in the distribution of lobes between different syndromes(P>0.05).The most(P<0.05)of pleural effusion was found in the damp heat syndrome.Conclusion:1.Children with severe MPP can be found in children of all ages,mainly3+-7 years old(preschool children).The incidence is not affected by gender.The onset season is mostly in autumn and winter(Ji’nan area).2.Children with severe MPP have TCM Syndromes of damp heat,closed lung syndrome and phlegm heat blocking lung syndrome.The incidence of syndromes is independent of sex.Damp heat and closed lung syndrome and phlegm heat blocking lung syndrome are mostly occurred in preschool children,mainly in autumn and winter.3.In children with severe MPP,the body temperature is mainly in the middle and high fever.The damp heat in the lung is more obvious than that in the other syndromes.The degree of cough and asthma is serious.Early lung auscultation is atypical.It is easy to be neglected in clinical practice,resulting in delayed treatment.4.Most children with severe MPP had mixed infection,mainly combined with virus infection.White blood cell count was mostly normal high value,C reactive protein and lactate dehydrogenase increased significantly.5.The changes of MPP imaging in children were large in large size,and the most of the hydrothorax in the damp heat closed lung syndrome.