| Objective:Retrospective analysis of clinical data of inpatients suffering from acute cerebral infarction,and explore the risk factors of acute cerebral infarction,the relationship between clinical examination indexes and acute cerebral infarction,and evaluate the therapeutic effect of thee kinds of drugs therapeutic schemes commonly used at present,so as to provide some basic research basis for clinical doctors to formulate prevention and control strategies for cerebral infarction.Method:Collecting and sorting out the medical cases data of 754 inpatients with acute cerebral infarction in a third-class hospital in qiqihar,heilongjiang province,from 2016 to 2017,Statistical and analysis clinical data of those inpatients including General demographic data and risk factors of infarction.Based on conventional treatment methods,according to the treatment method of patients,754 patients with acute cerebral infarction were divided into three groups: aspirin + clopidogrel group(389cases),bartrexine + aspirin group(173 cases),and aspirin + clopidogrel + bartrexine group(192 cases).First,the differences in general clinical data,high-risk factors of cerebral infarction and clinical examination indexes between the three treatment groups were compared.Further,the improvement of neurological function of patients with three different treatment regimens were evaluated according to the NIHSS scores of patients with acute cerebral infarction before and after treatment,and the improvement of main clinical symptoms of patients were evaluated according to the ADL scores.Result:1.General demographic characteristics of cerebral infarction: the onset age in 754 cases of patients with acute cerebral infarction was mainly between 45 and 74 years old,the lowest age was only 24 years old,the highest age was 81 years old.Theincidence rate in females(38.86%)was significantly lower than that in males(61.14%).2.Risk factors analysis result of acute cerebral infarction patients: among the 754 patients,the highest proportion of patients with hypertension history was 65.78%,followed by smoking history(47.88%),history of coronary heart disease(24.14%),history of diabetes(20.56%),history of cerebral infarction(11.94%)and hyperlipidemia(1.33%).3.The main clinical examination items analysis result of acute cerebral infarction patients : among the 754 patients,the electrocardiogram examination showed the most common abnormality(n?=?685,90.85%)ST,while only 29 cases(3.85%)werenormally;the multiple plaques in the internal carotid artery system were mostly appearence(n=654,86.74%),while only 29 cases(3.85%)were single plaques;the The subclavian artery system plaque were mostly singal(n=166,22.02%),while only261 cases(34.62%)were multipleplaques and 309 wrer normal cases(40.98%),7cases of arterial stenosis(0.93%),and 5 cases of vascular occlusion(0.55%);there were 536 cases(71.09)of infarction in cerebral hemisphere,accounting for71.09%,while 118(15.65)cases were found in the brain stem;Results of plain scanning and DWI showed that there were 109 cases(15.65)of frequent occurrence,while 645 cases(85.54%)of solitary occurrence;The results of magnetic resonance angiography showed that 109 cases were not abnormal,accounting for14.46%,645 cases with arteriosclerosis,accounting for 85.54%,20 cases with occlusion,accounting for 2.65%,and 106 cases with stenosis,accounting for 14.06%.4.The results showed that the NIHSS score of batroxobin +aspirin group after treatment was 2.73±1.443,significantly lower than the previous 4.62±1.119,P < 0.05,and the difference was statistically significant.After treatment,the NIHSS score of batroxobin + clopidogrel was 2.82±1.410,significantly lower than that of 4.71±1.195,P < 0.05,and the difference was statistically significant.The NIHSS score of aspirin +clopidogrel + batroxobin group after treatment was 2.84±1.314,significantly lower than 4.77±1.171,P < 0.05,and the difference was statistically significant.The NIHSS scores of the three treatment groups before and after treatment were compared,both showing a statistically significant difference(P>0.05).5.Three treatments of patients with acute cerebral infarction clinical improvement evaluation results: showed that Batroxobin + aspirin group with the useof antiplatelet drugs has 357 patients(96.4%)improved,the song of bartrexine+clopidogrel group of 164 patients(94.8%)improved,aspirin + clopidogrel +batroxobin group of 185 patients(96.4%)improved,there was no statistically significant difference(P > 0.05).Conclusion:1.Male patients with acute cerebral infarction accounted for 61.14% of a hospital in Qiqihar,and the age of onset was mainly between 45 and 74 years old.2.Acute cerebral infarction with hypertension accounted for 65.78% in a hospital in Qiqihar.The plaque of the internal carotid artery system is mainly multiple;the plaque of the subclavian artery system is mostly multiple;the infarction site is mainly the single lesion of the cerebral hemisphere.3.The three treatment regimens in this study have a good effect on the neurological function of patients with acute cerebral infarction,and there is no difference in adverse events. |
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