| ObjectiveTo investigate the diagnostic performance of DKI for distinguishing lymphoma and NPC metastases involving the head and neck lymph node.Methods and MaterialsBetween February 2016 and December 2017,30 patients with lymphoma,44 patients with NPC metastatic lymph node and 37 healthy volunteers with benign lymph node were enrolled prospectively.All lymphoma and metastases were pathologically confirmed.Benign lymph nodes were followed-up for 6 months and had no obvious change.All subjects were accepted DKI and DWI scan at 3.0 Tesla MRI（Achieva TX,Philips Healthcare,Best,The Netherlands）.The Apparent diffusion coefficient（ADC）value,diffusion coefficient（D）value and kurtosis（K）were measured and compared among three groups.The results were analyzed statistically,receiver operating characteristic（ROC）curve was described to evaluate the diagnostic capability of ADC,D and K.The diagnostic threshold,sensitivity and specificity of DKI for head and neck lymphoma were acquired.ResultsADC and D values of head and neck lymphoma were significantly lower than NPC metastatic lymph node(0.65±0.15 vs.0.83±0.17×10-3mm/s2 and 0.78±0.11 vs.1.05±0.17×10-3mm/s2,respectively),also lower than benign lymph nodes(1.02±0.11and 1.37±0.18×10-3mm/s2).While the K values of head and neck lymphoma were significantly higher than NPC metastatic lymph node（1.05±0.20 vs.0.96±0.26,p<0.05）,also higher than benign lymph nodes（0.88±0.16）.ROC curve indicated the area under the curve（AUC）of ADC,D and K value was 0.803,0.918 and 0.408,respectively.CONCLUSIONThe D value of DKI is superior to ADC value of DWI for diagnosing head and neck lymphoma.However,the diagnostic value of K remains to be further explored. |
PDF Full Text Request