Analysis Of Preoperative EEG In Glioma Patients

Objective to analyze the changes of eeg in patients with glioma and analyze the risk factors of preoperative epileptic discharge.Methods: the clinical data of 58 cases of glioma treated by the affiliated hospital of fujian medical university from 2012 to 2014 were retrospectively analyzed,and the results of video electroencephalogram were retrospectively analyzed.Preoperative routine perfect head MR and CT examination in the diagnosis of intracranial space-occupying lesions,postoperative pathology confirmed for glioma,and to measure the tumor diameter,place,and whether tumor weeks edema,ask for details of the history,and extract the gender,age,whether preoperative seizu res,tumorsize,pathologic stage,tumor weeks whether edema,and whether tumor involving the cortex chi-square test for single factors,C value and the OR value calculation,the above factors and glioma preoperative electroencephalogram in epilepsy wave(spike wave,sharp wave,slow spines composite wave,pointed the slow composite wave,many spines composite wave paroxysmal abnormal),the relationship between multiple factors analysis using unconditioned Logistic regression analysis,to study the independent risk factors.Results there were 8 abnormal cases,abnormal rate was 86%,8 cases were mildly abnormal and 42 were moderately abnormal.There were 29 cases of frontal lobe,8 cases of frontotemporal boundary,10 cases of temporal lobe,11 parietal lobe,and 41 cases(70%)were able to distinguish the lesions,and 17 cases were not judged.Electroencephalogram background wave changes characterized by basic frequency is irregular,mixed and disorderly,mixed with wave,abnormal wave mainly for focal high amplitude slow wave 45 cases(78%)or diffuse high amplitude slow wave and localized epilepsy wave of 39 cases(67%).Low grade gliomas more characterized by focal abnormal,slow wave often in a theta range,high grade glioma especially glioblastoma abnormal wave is relatively broad,can appear extremely slow activity or low-rising slow activity with high amplitude activity decreases quickly.Single factor analysis found that seizures,pathological level,tumor weeks edema,tumor involving the cortex associated with the incidence of preoperative glioma patients with epilepsy wave(P < 0.05),factors such as age,sex,tumor size,there was no significant difference(P > 0.05).Logistic regression analysis indicated that the history of epilepsy,tumor involvement and cortex were independent risk factors,and the pathologic level was independent protection factor.Conclusion patients with glioma 24 hours long-range video electroencephalogram of combining relevant imaging examination can help the diagnosis and localization of intracranial glioma,and the nature of glioma has certain reference value.Patients with glioma have a history of epileptic seizures,glioma,and obvious edema,and low pathologic grade is more likely to induce seizures.According to these factors,clinical perioperative treatment to prevention and control of glioma patients with seizures,ultimately achieve the purpose of double treatment of tumor with epilepsy,and then improve the patients quality of life.