| Tumor patients,especially those before and after perioperative period,are prone to lack of physical function due to nutrient deficiency.On the one hand,cancer patients or patients with digestive digestive tract tumors lack long-term dietary supplements,resulting in accelerated glucose decomposition,slow muscle synthesis,and weight loss.At the same time,the growth of tumors can lead to metabolic abnormalities in cancer patients,resulting in malnutrition in the body.On the other hand,the surgical procedures,chemotherapy,and radiotherapy involved in the treatment of cancer patients will consume nutrients of tumor patients in varying degrees.Nutritional therapy plays an important role in the treatment of cancer patients and is an important part of the treatment process for cancer patients.Enteral nutrition is the carrier of nutritional treatment for cancer patients.Through the amino acid score,P.aibuhitensis first limit and the second limiting amino acid,valine and cysteine and methionine + CS scores the first limit and the second limiting amino acids,cysteine and methionine + valine.Three different levels of AAS nereid EN preparations score first limit and the second limiting amino acids,cysteine and methionine + valine,CS scores the first limiting amino acid for the cysteine and methionine + the second limiting amino acids valine,understanding of the limiting amino acid powder and silkworm sand EN preparations,can reasonable collocation food,raise the utilization ratio of food proteins.The enteral nutrition formulation with terrestrial biological resources plays an important role in providing nutrient requirements for tumor patients.Compared with terrestrial animals,the marine animal protein that is closer to the body's amino acid nutritional composition ratio may be obtained as an enteral nutritional preparation component.will probably get better tumor enteral nutrition preparations.The nutritional components of the P.aibuhitensis were measured and analyzed in the early stage of the laboratory.with different varieties and regional nereid and other aquatic products,understand the bidentate reflected area around sand of P.aibuhitensis protein accounted for 68% of the dry Weight of the P.aibuhitensis,containing 17 kinds of essential amino acids the human body needs,tryptophan because its in the determination of the hydrolysis process,then cannot be checked out.The ash content was 7.4 ~ 7.8g/100 g,and the proportion of essential The amino acid in the total amino acid was as high as 46.61% ~ 47.21%.The ratio of essential amino acids to non-essential amino acids is 87% ~ 89%.In addition,P.aibuhitensis are rich in minerals,DHA and EPA are also high.Heavy metal elements are low in content.Therefore,the high protein content of Marine animals can be used as a protein source for special medical use formula,and has broad prospects for development.Nutritional characteristics of intestinal nutrition in P.aibuhitensis.The composition of amino acid composition,fatty acid composition,mineral element content and heavy metal content of the intestinal nutrition preparation were determined and the rationality of the formulation was evaluated.Reference to national standard GB/T 5009.124 2003 amino acids,the acid hydrolysis method,P.aibuhitensis powder and P.aibuhitensis enteral nutrition preparations of the proportion of the total number of amino acids,essential amino acids,respectively,46.47%,50.05%,50.42% and 53.76%,the ratio of the total number of essential amino acids and non-essential amino acids was 0.87,1.00,1.02 and 0.87,respectively,were higher than the WHO/FAO reference model(1973);Fatty acid composition by reference to national standard GB/T 9695.2 2008,using gas chromatography determination,P.aibuhitensis of DHA and EPA in enteral nutrition preparations of the unsaturated fatty acid,respectively,34.93%?33.85%? 32.76%,a-linolenic acid and n-6 linoleic acid content of the unsaturated fatty acid respectively 58.84%?62.18%? 62.28%;Mineral elements Fe,zinc,Mn content determination by graphite furnace AAS method,element Se by atomic fluorescence spectrometry,and the results show that Fe element content in P.aibuhitensis to meet the needs of tumor patient of Fe element,zinc,Mn and Se need extra in formula;The content of heavy metal Cd,Cr,Pb,determination by graphite furnace AAS method,metal Hg content by atomic fluorescence spectrometry,the results showed that detect the four kinds of heavy metal content in P.aibuhitensis of general principles of the special medical restrictions on tumor patients with enteral nutrition preparations.Gastroenteric digestion characteristics of enteral nutrition agents.AAS and CS score,all essential amino acids in the P.aibuhitensis were lower than the FAO/WHO standard model.In the process of digestion and digestion of gastrointestinal tract,the protein of sericin and sericulture have high digestibility and high absorption rate,which indicates that the protein can be digested and treated well in human body.Nutrition intervention of enteral nutrition agents in P.aibuhitensis.With diethyl nitrosamine and preparation before early hepatocellular carcinoma lesions induced mouse model,set up the P.aibuhitensis sand processing group,positive control group(A,B,C)(D)(E),blank group and the control group(F).To deal with 4 weeks,observe the weight change of the model mice,Serum nutritional indicators,immune indicators,inflammatory markers,liver function indexes were detected and liver pathological changes were observed.The weight of mice increased gradually during the treatment of enteral nutrition in perinereis aibuhitensis.For D28,the weight of group A was 61.49% higher than group E;The contents of TP and Alb of group A were significantly higher than group E,while lower than F group.Group A increased by 30.32% and 13.68% separately.For D7,D14,D21 and D28,the TNF-? level of group A was obviously lower than group E.For D28,group A decreased by 30.15% when compared with group E;Group A had a significantly higher level of IL-2 than group E.For D7,D14,D21 and D28,the ALT and AST levels of group A markedly decreased compared with group E.For D 28,group A were 83.75% and 128.20% lower respectively.Group A had good histological features of liver tissue compared with group E.When perinereis aibuhitensis was used as protein source of enteral nutrition,the special medical purpose formula can promote the synthesis of TP and Alb in the liver of precancerous lesions of experimental animals,and improve the nutritional metabolism of liver precancerous lesions in mice.It can also relieve the inflammation of TNF-?,IL-2 in liver precancerous lesions experimental animals,as well as the liver tissue morphological damage reflected by ALT and AST.When the protein content of silkworm was 60% of the total protein of enteral nutrition,the nutritional effect of the perinereis aibuhitensis enteral nutrition formula was significant.P.aibuhitensis is rich in nutritive value,with a high protein content of 68%.It has high absorptivity and high efficiency,which is suitable for the protein source of enteral nutrition.The immunological index and nutrition index of enteral nutrition for the tumor patients were improved,and the inflammation index and liver function index were controlled.There are many academic values worth developing,and the market development prospect is broad,which needs further study and discussion. |
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