| Objective: Ventilator-associated pneumonia(VAP)caused by Acinetobacter baumannii is common in intensive care unit.The aim of this study was to identify predictors of 28-day mortality in these patients.To identify high risks earlier and prevent earlier for reducing the incidence rate and mortality.Methods: We conducted a single center retrospective study at Intensive Care Unit of Tongji Hospital affiliated to Tongji Medical College Huazhong University of Science and Technology.This study included 107 patients diagnosed Acinetobacter baumannii ventilator-associated pneumonia between September 2014 and May 2016.Medical records of these patients were reviewed using electron medical record system and important information were recorded in EXCEL and SPSS.Predictors of 28-day mortality were analyzed using multivariable logistic regression adjusted for possible confounders with SPSS 20.0 statistical software.Results: This study detected the mortality rate of Acinetobacter baumannii ventilator-associated pneumonia was 55.14% in Tongji Hospital intensive care unit.The independent risk factors of 28-day mortality were APACHE II on admission in ICU[OR=1.124,95%CI 1.025-1.231,P=0.013]?CPIS when diagnosed Ab-VAP [OR=1.748,95%CI 1.051-2.906,P=0.031] ? the use of vasoactive drugs [OR=8.124,95%CI1.558-42.364,P=0.013].The time stay in ICU [OR=0.832,95%CI 0.709-0.976,P=0.024]was protective factor for 28-day mortality.Further analysis of ROC curve,we conducted APACHE II >23 on admission and CPIS>7 when diagnosed Ab-VAP were prognostic risk factor for 28-day mortality.Conclude: The mortality rate of Acinetobacter baumannii ventilator-associated pneumonia in our ICU was really high and the patients commonly had a poor outcome.The independent risk factors of 28-day mortality were APACHE II>23 on admission in ICU?CPIS>6 when diagnosed VAP ? the use of vasoactive drugs.The time stay in ICU was protective factor for 28-day mortality. |
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