The Correlation Between BRVO And The Degree Of Rteriosclerosis And TCM Syndrome Differentiation

Objective: To study the correlation between BRVO and the degree of arteriosclerosis and TCM syndrome differentiation.Research methods: This study adopts a retrospective analysis method.Selection in June 2015 to D ecember 2017 in chengdu university of traditional Chinese medicine hospital di agnosed with branch retinal vein occlusion(branch retinal vein occlusion,BRV O)in patients with 35 cases(35 eyes),to select 35 cases(35 eyes)of control group ccordance with the inclusive criteria.Collect patient's general condition,eye examination,laboratory examination results,TCM syndrome.Measurement and analysis of the binoculareyes with BRVO group and Random monocular with control group(using Heidelberg automatic measurement tools:(1)In the fundus fluorescein image,The diameters of the arteriovenous vessels at four quadran ts that of the range of the distance between edge of the optic disc 0.5DD-1D D(1DD equal to optic disc diameter).The measured data generation into the modified Parr-Hubbard formula to calculate the equivalent of central retinal a rtery diameter(central retinal artery equivalent,CRAE),the equivalent diameter of central retinal vein(central retinal venular equivalent,CRVE),and arteriove nous ratio(artery-vein thewire,AVR).(2)Subfoveal choroidal thickness(SFC T).(3)Central fovea thickness(CFT).Analysis of the difference of two groups of retinal vascular diameter,choroid thickness,central fovea thickness and the d egree of arteriosclerosis and the characteristics of TCM syndromes.Research results: 1.In the 35 cases of BRVO group,21 cases of retinal atherosclerosis were observed in the fundus images,accounting for 60% of the total samples,and 14 cases without retinal atherosclerosis,accounting for 40% of the total samples.2.There were 35 cases in BRVO group,In the 35 injured eyes,there were 6 cases of AVR < 1/2,with a total of 16 cases of AVR between 1/2 and 2/3,with 13 cases of AVR greater than 2/3,accounting for 17.1%,45.7% and 37.1% respectively.In the 35 healthy eyes of BRVO group,there were 2 cases of AVR between 1/2 and 2/3,accounting for 5.7% of the total,and 33 cases of AVR were greater than 2/3,accounting for 94.3% of the total.There were 35 cases in the control group,there were 2 cases of AVR between 1/2 and 2/3,accounting for 5.7% of the total,and 33 cases of AVR were greater than 2/3,accounting for 94.3% of the total.3.The values of the BRVO group in the injured eyes of CRAE,CRVE,AVR,SFCT and CFT were:(109.23±16.87)?m?(174.85±30.34)?m?0.64±0.11 ?(259.46±92.74)?m?(488.51±169.87)?m;The above values of the BRVO group In the 35 healthy eyes were respectively :(131.05±18.25)?m?(165.63±30.73)?m?0.80±0.11?(205.63±66.61)?m?(246.81±100.53)?m;The above values of the control group were :(125.26±13.56)?m?(155.43±14.96)?m?0.81±0.08?(218.99±74.59)?m?(225.16±29.55)?m 4.The difference between the injured eyes and the healthy eyes in BRVO group was statistically significant(P < 0.05),and the difference in CRVE was not statistically significant(P < 0.05).5.Compared with the injured eyes in BRVO group and control group,CRAE,CRVE,AVR,SFCT and CFT were all statistically significant(P < 0.05).6.Compared with the healthy eyes in BRVO group and control group,,there was no significant difference in CRAE,CRVE,AVR,SFCT and CFT(P>0.05).7.In 35 cases of BRVO,there were 22 cases of qi stagnation and blood stasis,accounting for 63% of the total.There were 11 cases of yin deficiency yang excess type,which accounted for 31% of the total.There were 2 cases of phlegm and blood stasis type,accounting for 6% of the total.TCM syndromes of BRVO patients: qi stagnation and blood stasis syndrome,>yin deficiency yang excess type > phlegm and blood stasis type.8.FOR these values of CRAE,CRVE and AVR,there were no statistically significant differences between the three TCM syndromes in the BRVO group,such as(P>0.05).9.The occurrence of retinal arteriosclerosis in BRVO group was not significantly correlated with gender,age,SFCT and CFT(P>0.05).10.Among the 35 cases of BRVO,23 patients with hypertension,11 cases with hyperlipidemia,7 cases with coronary heart disease,accounting for 65.70%,31.40% and 20.00% respectively.There were 21 cases of retinal arteriosclerosis in BRVO group,19 of 21 patients with hypertension,8 cases with hyperlipidemia,5 cases withcoronary heart disease,accounting for 90.50%,38.10%,23.80% respectively.Conclusion: 1.More than half of BRVO patients developed retinal arteriosclerosis.2.Judgment of retinal arteriosclerosis,qualitative judgment and quantitative judgment results are different,the main reason of which is the difference of measurement sites.3.The arteriosclerosis of BRVO was significantly increased compared with that of contralateral healthy eyes.4.The SFCT and CFT of BRVO were significantly increased compared with that of contralateral healthy eyes.5.However,there was no difference in the degree of retinal arteriosclerosis,CRAE and CRVE among the three types of TCM syndromes of BRVO.6.There was no significant correlation between the incidence of retinal arteriosclerosis in BRVO and gender,age,SFCT and CFT.7.Systemic diseases such as hypertension,hyperlipidemia and coronary heart disease are risk factors for BRVO.