The Analysis Of Related Factors Of Neonatal Intracranial Hemorrhage

Intracranial hemorrhage(ICH)is a common cause of neonatal brain injury disease,more common in premature and low birth weight infants,the incidence of term infants is relatively low.Periventricular-intraventricular hemorrhage is a common intracranial lesion in preterm infants.It is closely related to the anatomy and physiology of the central nervous system in preterm infants and the immature neurobiological development.Studies have shown that there are a variety of high-risk factors to promote its occurrence and development.Severe intracranial hemorrhage can lead to different degree of nervous system sequelae,such as hydrocephalus,cerebral palsy,movement and intelligent backwardness,etc.Therefore,early prevention and recognition of neonatal intracranial hemorrhage are particularly important.This study analyzed the factors associated with intracranial hemorrhage in newborns and provided the clinical basis for the early prevention of this disease.Objective:This article provides a reference for early recognition and prevention of the intracranial hemorrhage in neonate by studying the related risk factors and identifying independent risk factors associated with the disease.Methods:The study group consisted of 150 neonates who were admitted to our department of neonatology and had intracranial hemorrhage confirmed by brain ultrasound from January 2016 to September 2017.During the same period,100 neonates confirmed to have no intracranial hemorrhage by cerebral ultrasound were selected as the control group.Analyzed the clinical data of 250 research objects,applied spss19.0 software to process data.Measured data were expressed as mean ± standard deviation.Independent sample t test was used for comparison between groups.Enumeration data were expressed as percentages and rates,?2 test was used for comparison between groups.Then binary logistic regression analysis was performed on the variables that were statistically significant in the univariate analysis.Results:1.After univariate analysis showed that the mother had gestational hypertension syndrome,gestational age less than or equal to 30 weeks,low birth weight,fetal distress,umbilical cord around the neck,placental abruption,postnatal asphyxia,metabolic acidosis,the presence of patent ductus arteriosus,application of dopamine,mechanical ventilation,and prolongation of APTT were different between the two groups,P<0.05.2.After multivariate regression analysis showed that: gestational age less than or equal to 30 weeks,neonatal asphyxia,fetal distress,application of dopamine and prolongation of APTT were independent risk factors for intracranial hemorrhage in newborns.Conclusion:Small gestational age,fetal distress,postnatal asphyxia,application of dopamine,and APTT prolongation are independent risk factors for intracranial hemorrhage in newborns.Reducing premature birth,avoiding asphyxia,hypoxia,reducing dopamine application,and actively improving coagulation function can reduce neonatal intracranial hemorrhage.