The Clinical Study Of Treating The Neurologic Impairment After Spinal Cord Injury With Tonifying Spleen And Stomach

ObjectiveThe purpose of this study is to treat the Spinal Cord Injury by tonifying spleen and stomach,and observe the recovery of neural function after Spinal Cord Injury by the use of Longqiqiangji Decoction and it's security.It also aims to provide clinical evidence for the treatment of spinal cord injury by tonifying spleen and stomach and to expand the thought of treating such diseases for Chinese medicine.MethodsDivided the 40 Spinal Cord Injury patients,who had been in treatment in Zhongshan Hospital of TCM affiliated to Guangzhou University of TCM during May 2017 to January 2018,into the treatment group and the control group randomly.The control group was treated with oral mecobalamin and general rehabilitation,and the treatment group was treated with oral mecobalamin,general rehabilitation and Longqiqiangji Decoction which was used once a day.Both two groups were treated 3 months.And compared the ASIA sensory function scores,ASIA motor function scores,FIM sores,somatosensory evoked potential(SEP),TCM syndrome scores and security before,after 6 weeks and 3 months of the treatment by the use of Statistics.Result1.Both two groups of ASIA sensory function scores were analyzed by repeated measure ANOVA?Inter group contrast:there was no significant difference in ASIA sensory function between two groups before the treatment(P>0.05),and the scores of treatment group were higher than the control group with statistical significance(P<0.01)after 6 weeks and 3 months of the treatment.Intra group contrast:the scores of treatment group after 6 weeks and 3 months were significantly higher compared with the scores before the treatment(P<0.05),and there had any significant difference between the scores before and after 6 weeks of the treatment in the control group(P>0.05)while the score after 3 month were higher than that before treatment with statistical significance(P<0.01).2.2.Both two groups of ASIA motor function scores were analyzed by repeated measure ANOVA?Inter group contrast:there was no significant difference in ASIA motor function scores between two groups before the treatment(P>0.05),and the scores of treatment group were higher than the control group with statistical significance(P<0.01)after 6 weeks and 3 months of the treatment.Intra group contrast:the scores of treatment group after 6weeks and 3 months were significantly higher compared with the scores before the treatment(P<0.05),and there had any significant difference between the scores before and after 6 weeks of the treatment in the control group(P>0.05)while the score after 3 month were higher than that before treatment with statistical significance(P<0.01).3.Both two groups of FIM scores were analyzed by repeated measure ANOVA?Inter group contrast:there was no significant difference in FIM scores between two groups before the treatment(P>0.05),and the scores of treatment group were higher than the control group with statistical significance(P<0.01)after 6 weeks and 3 months of the treatment.Intra group contrast:the scores of two groups after 6 weeks and 3 months were significantly higher compared with the scores before the treatment(P<0.05,0.01).4.Both two groups of SEP incubation period were analyzed by repeated measure ANOVA?Inter group contrast:there was no significant difference in SEP incubation period between two groups before the treatment(P>0.05),and the SEP incubation period of treatment group were shorter than the control group with statistical significance(P<0.01)after 6 weeks and 3 months of the treatment.Intra group contrast:the SEP incubation period of treatment group after 6 weeks and 3months were significantly shorter compared with the scores before the treatment(P<0.01)while that had no statistical significance in the control group.5.Both two groups of TCM syndrome scores were analyzed by repeated measure ANOVA?Inter group contrast:there was no significant difference in TCM syndrome scores between two groups before the treatment(P>0.05),and scores of treatment group were lower than the control group with statistical significance(P<0.01)after 6 weeks and 3 months of the treatment.Intra group contrast:the scores of two groups after 6 weeks and 3 months were significantly lower compared with the scores before the treatment(P<0.01).And The total effective rate of the treatment group was 100% while the control group was30%,and the comparison of TCM syndrome efficacy between the two groups has statistical significance(P<0.01).6.The indexes of security has no statistical difference between the two groups before and after treatment analyzed by repeated measure ANOVA(P>0.05).During the study period,3 patients had some mild vomiting which were able to relieve themselves.ConclusionThe Longqiqiangji Decoction which is composed by the theory of tonifying spleen and stomach can improve the patients' sensory function,motor function and the conduction of spinal sensory nerves,and it is able to improve their independence of daily-life and enhance their quality of life.Also,The Longqiqiangji Decoction can improve the symptoms of weakened spleen and stomach such as lack of energy,poor appetite and yellow complexion.We can come to the result that tonifying spleen and stomach will improve the patients' neural function,clinical symptoms and the quality of daily life after Spinal Cord Injury,and with well security.