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The Study Of Relationship Between The Risk Score Of Non-ST-segment Elevation Myocardial Infarction And Clinical Characteristics Of TCM Syndromes

Posted on:2019-04-26Degree:MasterType:Thesis
Country:ChinaCandidate:H M LiFull Text:PDF
GTID:2404330548485397Subject:Internal medicine of traditional Chinese medicine
Abstract/Summary:
Objective:The objects of this study were NSTEMI patients,by studying the correlation between the TCM syndrome and risk score,figure out the impact of risk scroe to the TCM syndrome distribution,summed up the impact of each syndrome factor for the risk scroe and the prognosis of NSTEMI patients,To help clinicians make a diagnosis and give treatment of NSTEMI patients.Methods:Use the method of investigative study,include 118 NSTEMI patients,collecting the clinical syndrome elements,and divide them into groups based on TCM syndrome types.Record the informations of patients,include:the general information,past medical history,TCM syndrome type.Then record the TIMI risk score,the GRACE risk score,PURSUIT risk score.With the risk score and syndrome elements as variables,analyse the distribution factors of the TCM symptoms.At last,we analyse the leading symptoms.Results:TCM syndrome total 297 times in 118 cases of patients.81(68.6%)times of blood stasis syndrome,41(34.7%)times of phlegm syndrome,19(16.1%)times of Qi stagnation,13(11.0%)times of coagulated cold syndrome,54 cases(45.7%)times of Qi deficiency,47(39.8%)times of Yin deficiency,37 cases(31.3%)Yang deficiency and 5(4.24%)blood deficiency.Blood stasis,phlegm syndrome,Qi deficiency appear more frequently,blood deficiency appears least.There was a statistically significant difference between each syndrome and the risk score(P<0.05).The distribution of TCM syndrome elements in non ST segment elevation acute myocardial infarction is mainly manifested by the increase of risk level.The syndrome elements are:blood deficiency,phlegm syndrome,Yang deficiency,Qi deficiency,blood stasis,yin deficiency,qi stagnation and cold coagulation.The distribution of TCM syndromes of NSTEMI is mainly manifested by the increase of risk level.The syndromes are in this order:blood deficiency,phlegm syndrome>Yang deficiency,Qi deficiency,blood stasis>yin deficiency>Qi stagnation and coagulated cold syndrome.These seven syndromes in NSTEMI patients are more common,which are Qi stagnation and blood stasis syndrome,Qi deficiency and blood stasis syndrome,Yin deficiency and blood stasis syndrome,Qi deficiency phlegm blood stasis syndrome,Yang deficiency phlegm blood stasis syndrome,Qi Yin deficiency and phlegm syndrome,Yin Yang deficiency and blood stasis syndrome.Spearman correlation detection showed that the correlation between syndrome types and risk score:TIMI score is not significantly correlated with the syndrome types(correlation coefficient =0.236,P=0.058),but GRACE score is significantly correlated with the syndrome types(correlation coefficient =0.575,P=0.00),and the PURSUIT risk score is significantly correlated with the syndrome types(correlation coefficient =0.474,P=0.00).Qi deficiency and phlegm blood stasis syndrome,Yang deficiency phlegm blood stasis syndrome,Qi yin deficiency and phlegm syndrome,Yin Yang deficiency and blood stasis syndrome are high risk syndromes,while Qi stagnation and blood stasis syndrome,Qi deficiency and blood stasis syndrome types,Yin deficiency and blood stasis syndrome are low risk syndrome types.Conclusion:1.The distribution of NSTEMI syndrome type has characteristics,and it mainly based on deficiency in origin and enrichment in symptom.The main syndromes are blood stasis,phlegm syndrome,Qi deficiency of,Yin deficiency and Yang deficiency.2.The syndrome distribution of NSTEMI risk score has characteristics.blood deficiency,phlegm syndrome>Yang deficiency,Qi deficiency,blood stasis>yin deficiency>Qi stagnation and coagulated cold syndrome.Qi deficiency and blood stasis exists in almost all patients;patients with Qi stagnation,coagulated cold syndrome had lower risk,and better prognosis;the patients with phlegm symptoms,Yang deficiency and yin deficiency symptoms had higher risk the patients with blood deficiency syndrome had a very high risk level that should be paid enough attention,and be given timely treatment.3.The GRACE score and PURSUIT score correlated well with Qi stagnation and blood stasis syndrome,Qi deficiency and blood stasis syndrome,Yin deficiency and blood stasis syndrome,Qi deficiency phlegm blood stasis syndrome,Yang deficiency phlegm blood stasis syndrome,Qi Yin deficiency and phlegm syndrome,Yin Yang deficiency and blood stasis syndrome.TIMI score is not significantly correlated with them.4.Patients with Qi deficiency phlegm blood stasis syndrome,Yang deficiency phlegm blood stasis syndrome,Qi Yin deficiency and phlegm syndrome or Yin Yang deficiency and blood stasis syndrome,the risk is higher,the prognosis is worse.They need timely treatment.Patients with Qi stagnation and blood stasis syndrome,Qi deficiency and blood stasis syndrome or Yin deficiency and blood stasis syndrome the risk is lower,the prognosis is better.
Keywords/Search Tags:NSTEMI, Risk score, Traditional Chinese medicine syndrome, Syndrome distribution, Correlation analysis
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