Clinical Observation Of Recovery Of Visual Function And Macular Anatomy In Patients With Idiopathic Macular Epiretinal Membrane After Early Surgery

Objective:In this study,multifocal electroretinography and optical coherence tomography were used to evaluate the recovery of visual function and macular anatomy in early postoperative patients with idiopathic macular epiretinal membranes.Method:30 patients with idiopathic macular epiretinal membrane(30eyes),among which BCVA≥0.5 was group A,and BCVA<0.5 was group B.There were 15 members in Group A,7 males and 8 females,and 15 in Group B,including 9 males and 6 females.The best-corrected visual acuity(BCVA),central Fovel Thickness(CFT),central Retinal Thickness-1mm(CRT),inner Retinal Thickness(IRT),outer Retinal Thickness(ORT),central Retinal Volume-1mm(CRV)and mfERG 1 ring P1amplitude density,P1 latency,N1 amplitude density,N1 latency were observed and recorded before surgery.Data of two groups was analyzed and compared.Result:Compared with before surgery,BCVA in group A decreased first and then increased to preoperative level.There was no significant difference in BCVA at 3 months after operation compared with preoperative.The visual acuity of group B was significantly higher than that before surgery,and the BCVA(logMAR)was changed from 0.76±0.18 preoperatively to0.29±0.14 postoperatively.The difference was statistically significant compared with preoperative.The CFT,CRT,and IRT were gradually decreased in both groups within 3 months after operation.The CFT in group A decreased from 448.82±95.55um before surgery to 377.64±79.71um,and the CRT decreased from 377.64±79.71um before surgery to 407.36±45.71um.IRT decreased from 363.36±80.15 um before surgery to 301.81±55.30 um;In Group B,CFT decreased from 531.08±106.66 um before surgery to 440.23±67.42 um,and CRT decreased from 515.62±90.84 um before surgery to 435.23±50.63um.IRT decreased from 419.92±95.71um before surgery to 350.31±51.85um,and there was a statistically significant difference compared with preoperative.No significant difference in ORT thickness at 3 months after surgery compared with preoperative.The amplitudes of P1 amplitudes at the 3rd month after surgery in A and B groups increased from 63.30±22.26nv/deg~2 and 51.93±21.76nv/deg~2 to 86.10±24.59nv/deg~2 and 73.36±17.15nv/deg~2.The amplitude of P1 amplitude at the third month postoperatively in the two groups of patients was statistically different.Correlation analysis showed that there was no significant correlation between BCVA at 3 months postoperatively and preoperative CFT,CRT,IRT,ORT,and mfERG P1 amplitude density,P1 latency,N1 amplitude density,and N1 latency.There was a correlation between BCVA at 3 months after surgery and BCVA before surgery(R=0.683,P=0.00).Patients with better vision before surgery can get better vision recovery after surgery.Result:Phacoemulsification combined with vitrectomy for idiopathic macular epiretinal can reduce macular edema and improve vision.Early surgery helps patients get better visual function recovery.Preoperative BCVA is the best predictor of postoperative visual acuity and can be preoperatively based on patient BCVA Predicting the Recovery of Postoperative Visual Function in Patients.