Pharmaceutical Study Of Xiang Shao Capsule

The current subject involves the Pharmaceutical studies on the re-de-velopment of the listed species xiangshao particles,which can Smooth the liver qi,dispel distending pain,dispersing stagnated liver qi for regulating sto-mach,used in the treatment of women with premenstrual syndrome.The prescription composed of radix paeoniae alba,radix bupleuri,rhizoma ligustici wallichii,bitter orange,liquorice and other ingredients.This topic instructed by Chinese medicine theory,uses the modem pharmaceutical technology,To reform the original formulations,screening process,and the quality standard and stability.Due to many kinds of medicinal herbs in the prescription contains a large number of volatile oils,essential oils were extracted by steam distillation,different extracting time,the extraction of volatile oil quantity and determine the best method of extracting volatile oil,add five times the amount of the amount of medicine water,the extracting five hours.To compare N-LOK with P-CD on inclusion ability for the volatile oil in the xiangshao granule.Choosing inclusion rate as index,using orthogonal test method to research on three facts which are the proportion of oil to inclusion material,inclusion material to water and inclusion time.The inclusion rate of N-LOK modified starch under the best inclusion condition was 65.22%,?-CD was 86.63%.Properties of volatile oil didn't change during the inclusion process.To choose ?-CD as inclusion material of volatile oil in xiangshao granule.Extraction of volatile oil liquid with other herbs add water decoction.amount of paeoniflorin content as index,in times of water quantity,decoction time,number of decoction for factors,optimizing the best extraction process by orthogonal experiment,and through the comparison experiment and magnified experiment,the best condition of extraction process is:10 times the amount of water,decoction for 1 hour,decoction for 3 times.Paeoniflorin content,amount of as examining index,with the relative density of extract,alcohol sink after ethanol content,alcohol sink time to examine factors,through orthogonal test to select the best alcohol sinking process,and through the comparison experiment and magnified the best condition of alcohol sinking process is:liquid enrichment to relative density 1.20,adding ethanol to achieve 80%ethanol content and let stand for 12 hours.Compare common flow aid to Que capsule powder on the improvement of their liquidity,and the optimum flow aid for silica.Establish the quality standards of incense Que capsule includes the content of paeoniflorin determination method,radix bupleuri,rhizoma ligustici wallichii,thin layer identification method of hovenia dulcis,liquorice,appearance identification,inspection,etc.