Application Research Of Patient-Controlled Intrav Enous Analgesia On Postoperative Hypopnea Syndrome Surgery In Obstructive Sleep Apnea

Objective: To evaluate the efficacy and safety of patient-controlled intrav enous analgesia on postoperative hypopnea syndrome surgery in obstructive sleep apnea.Methods: 60 cases of postoperative hypopnea syndrome surgery in obstructive sleep apnea patients applied modified UPPP were randomly divided into experimental group and control group averagely;30 patients in the experimental group patients applied patient-controlled intrav enous analgesia were used drugs of sufentanil 0.002mg/kg,droperidol 0.1mg/kg,saline diluted to 100 ml,load capacity of 5ml,a single dosage of 0.5ml,continuous dosing speed of 2ml/h,lockout time 15min;30 patients in control group of patients were given nimesulide 0.1g for oral analgesia according to the requirements of patients;all patients were performed on postoperative VAS pain score and simplified McGill score,and observed by the effects of controlled intravenous analgesia on postoperative stress response.Blood serum concentrayions of C3?C4?CRP were mearsured before and at postoperative 24 h and 48 h.Results:Compared with the experimental group and control group,the VAS score of experimental group after postoperative 24 h were higher than the control group(P <0.05);Simplifying the McGill score after 48 h were higher than the control group(P <0.05);Elevated blood sugar after 8h magnitude were lower than the control group(P <0.05);The occurrence of adverse reactions were decreased in the control group(P <0.05).There was significant increase in the level of C3 and C4 in all groups comparing with the level before anesthesia(P<0.05),CRP in control group increased significantly compared with the experimental group at postoperative time point(P<0.05),C3 and C4 in the experimental group afterincreased significantly compared with the control group at postoperative time point(P <0.05).Conclusion: Application of patient-controlled intrav enous analgesia on postoperative hypopnea syndrome surgery in obstructive sleep apnea applied modified UPPP is effective and safe.