Guillain-barr(?) Syndrome:prognosis And Transform Of Electrodiagnosis Subtypes

Objective: The aim of this study is to observe the influence factor of Guillain–Barr(?) syndrome(GBS),to compare the differences between prognoses of demyelinating and axonal subtypes,and to study the transformation and meaning of electrophysiology classification.Methods: Creating a sample of 35 patients by using the epidata software,classifying patients into four different groups based on the results of electrophysiological investigation: acute inflammatory demyelinating polyneuropathy(AIDP)group,acute motor axonal neuropathy(AMAN)group,unclassified group and normal group.Utilizing Hughes GBS Disability Scale to monitor the data,11 patients complete the follow up of eletrophysiological investigation,and utilize SPSS24.0 software to analyze the result.Results: At the early stage,the score declines faster in AMAN group than AIDP group,P=0.022(P<0.05);To the contrary,in the terminal stage,the score declines faster in AIDP group,P=0.036(P<0.05).After 12 months,the score of the two groups are similar,P=0.62(P<0.05).With an improvement of the disease,more patients transform into unclassified group and normal group.Conclusion: AMAN improves faster at the early stage,however,AIDP improves faster in the long-term.At the terminal stage,the demyelinating and axonal characteristics of patients gradually fade away,there is no evidence of transformation between AIDP and AMAN.Therefore,long-term regular electrophysiological examination will not be necessary if there is no major relapse in the disease.