Retinal Vessel Oxygen Saturation In Liver And Kidney Deficiency Type High Myopia

Purpose:To investigate changes in retinal vessal oxygen saturation in liver and kid ney deficiency type high myopia.Methods:Relative oxygen saturation was measured in retinal blood vessels of 18 p articiPants with liver and kidney deficiency type high myopia and compared t o a control group of 20 individuals with healthy people with Oxymap T1 reti nal oximeter.Retinal images were collected in the darkroom by the same tech nologist.The measurement was repeated 2-3 times for each patient,and take a n average.Each eye selected a top quality image to detect the oxygen saturati on of retinal vessel which located in 1.5-3.0 disc diameter from the optic dis c.Data acquisition and image analysis were completed by another technologist.Results:For the high myopia patients,retinal arteriole?SaO₂?saturation?95.4±14.529%?and the difference in arterio-venous?Sa-vO₂?saturation?30.35±17.041%?were lower than in normal individuals?97.79±9.223%,32.74±11.277%?,but did not reach statistical significance?all p>0.05?.The saturation were similar in venul es of the high myopia?65.04±10.565%?and normal individuals?65.05±9.439%?.Arterial difference in oxygen saturation did not differ significantly?all p>0.05?be tween the fundus quadrants of the two groups.The venular?SvO₂?oxygen sa turation in the inferotemporal quadrant,High myopia group was higher than t he normal control group and the difference has statistical significance?p=0.014?.All the Sa-vO₂ high myopia group was lower than the control group except th e superonasal quadrant.And the values in the inferotemporal quadrant has sta tistical significance?p=0.013?.Mean SaO₂ was highest in the superonasal quadran t,followed by the inferonasal quadrant,the superotemporal quadrant and the inferotemporal quadrant.On the contrary,mean SvO₂ was highest in the infe rotemporal quadrant,followed by the superotemporal quadrant,the inferonasal quadrant and the inferonasal quadrant.Conclusion:1?There is a trendency that the arterial oxygen saturation in the high myopia patients were lower than the normal individuals.2?The SvO₂in the inferotemporal quadrant,High myopia group was hig her than the normal control group.3?In the correlation analysis,there did not find correlation between ox ygen saturation,age and diopter.