The Efficacy Of The Capsule Of Modified Ningshen Pellet In Treating ICU Delirium

Objective: To observe the combined with capsule of Modified Ningshen Pellet scheme of combining traditional Chinese and western medicine on the prognosis of delirium.Useing the scientific method to evaluate the role of capsule of Modified Ningshen Pellet in the treatment of delirium.Methods: Select the patients who were a clear diagnosis of delirium in Affiliated Hospital of Chengdu University of Traditional Chinese Medicine Critical Care Medicine from January 2016 to March 2017.Diagnostic criteria and selected accord with CAM-ICU met inclusion and exclusion criteria of delirium cases;Cases will be based on whether or not to use traditional Chinese medicine(TCM)capsule of Modified Ningshen Pellet is divided into experimental group(capsule of Modified Ningshen Pellet + standardized treatment of western medicine)and control group(medicine standardized treatment).Record of the Nursing Delirium Screening Scale(Nu-DESC)score,the number of delirium episodes,the accumulated time of delirium,the number of cases of delirium without recurrence,28 days mortality,mechanical ventilation duration and related laboratory tests.SPSS21.0 software was used for statistical analysis to observe whether observed indicator whether there are differences,and whether the difference is statistically significant.Results: A total of 40 patients were screened,with 20 in the treatment group and 20 in the control group.Age,sex,APACHE II score,the Nursing Delirium Screening Scale(Nu-DESC)score and related laboratory tests was not statistically significant different between two group.The accumulated time of delirium(3.355±2.897 vs 4.573±2.403,P=0.038)has statistically significance.The Nu-DESC score after treatment 3 days(1.75±1.74 vs 2.00±1.52,P=0.487),the number of delirium episodes(1.35±1.66 vs 1.10±0.85,P=0.955),the number of cases of delirium without recurrence(60% vs 30%,P=0.055),28 days mortality(20% vs 40%,P=0.168),mechanical ventilation duration(11.80±11.72 vs 7.60±8.54,P=0.242)was not statistically significant different between two group.Conclusion: The capsule of Modified Ningshen Pellet shorten delirium time.There was no significant influence on the Nursing Delirium Screening Scale(Nu-DESC)score,the number of delirium episodes,the number of cases of delirium without recurrence,28 days mortality,mechanical ventilation duration.