Study On The Distribution Of TCM Constitution In Patients With Ischemic Stroke (Recovery Period) Combined With Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS)

Objective:This study is based on the "treating disease before its onset" theory of TCM as a guide,with the foundation of TCM constitutional theory.By retrospective investigation of the TCM constitution in patients with ischemic stroke(recovery period)and OSAHS,objective to analyze the regularities of distribution and the relationship with modern medical indexes in patients with ischemic stroke(recovery period)and OSAHS and to provide evidence for the prevention and treatment of ischemic stroke and OSAHS.Methodology:In this study,patients with ischemic stroke(recovery period)and OSAHS who were admitted to the Affiliated Hospital of Chengdu University of TCM of neurology outpatient and inpatient department from November 2015 to November 2016 were enrolled in the study.By means of questionnaire survey,complete with "general information collection table" and "Chinese constitution table",and according to the standard of TCM Constitution,the constitution of the patients was classified.Fill in the "ESS" and "NIHSS" scale and establish a database.According to the principles and methods of clinical epidemiology,the relationship between the distribution of the TCM constitution and the modern medical indexes was studied.Outcome:1.The majority of patients with ischemic stroke(recovery period)and OSAHS were50 to 79 years old in the elderly.The ratio of male to female was 1.51:1.About 74% of the patients weight above normal.The severity of OSAHS is mainly mild and moderate.The disease is easy to combine with many kinds of diseases,among which hypertension,hyperlipidemia and diabetes are the main diseases.There was a significant difference in the gender distribution between smoking and drinking,but there was no significant difference in obesity.2.The TCM constitution of patients with ischemic stroke(recovery period)and OSAHS:Phlegm dampness constitution accounts for about 26%,Qi deficiencyconstitution accounted for 20%,Blood stasis constitution accounts for about 17%,Qi stagnation constitution and damp and heat constitution each account for about11%,Yang deficiency constitution accounted for about 5%,Yin deficiency constitution and normal constitution each accounted for about 4%,The special constitution accounts for about 2%.There is a big difference in TCM Constitution between the patients and the general population.3.Comparison of three types of risk factors,including smoking,drinking and obesity:There was no significant difference between the smoking/non-smoking group and the drinking / non-drinking group,but there was a significant difference in the distribution of TCM constitution between the obesity group and the non-obesity group(P<0.01).4.In the study of the relationship between TCM constitution and modern medical index:The average score of ESS score in phlegm dampness group was higher than that in non phlegm dampness group,and the difference was statistically significant(P<0.01);The mean rank of AHI in phlegm dampness group was higher than that in non phlegm dampness group,and the difference was statistically significant(P< 0.01);The mean rank of BMI in phlegm dampness group was higher than that in non phlegm dampness group,and the difference was statistically significant(P< 0.01);The mean rank of ESS score of qi deficiency group was higher than that of non Qi deficiency group,and the difference was statistically significant(P< 0.05);The mean rank of AHI in the blood stasis group was higher than that in the non blood stasis group,and the difference was statistically significant(P < 0.01).Conclusions:1.In patients with ischemic stroke(recovery stage)and OSAHS,phlegm dampness,Qi deficiency and blood stasis are the three main types of TCM Constitution.2.The main constitution type of obese patients is phlegm dampness;the main constitution type of non obese patients is deficiency of Qi,and secondly,blood stasis,phlegm and dampness are relatively more.3.Patients with phlegm dampness constitution and Qi deficiency constitution showed more severe degree of sleepiness;Patients with phlegm dampness constitutionand blood stasis constitution showed higher AHI index;Patients with phlegm dampness constitution showed higher body mass index.