To Investigate The Influencing Factors Of Neurological Ulcer The Risk Degree In DPN Patients And Its Relationship With TCM Syndromes

Purpose:Through the shock sensory threshold inspection results have been clearly diagnosed as diabetic peripheral neuropathy(DPN),there is no risk of stratum ulcer in patients with ulcer risk stratification.Collect patients' general information,Biochemical indexes(triglyceride,fasting blood-glucose).Explore the objective factors influencing risk stratification to facilitate the early prevention of DPN patients with neurological ulcers.we through exploring the impact of risk stratification of the objective factors in the DPN TCM syndromes whether exist differences,trying to elucidate the relevant pathological mechanism and guiding the clinical use of Chinese medicine combined with Western medicine means to monitor the intervention,to reduce the risk of neurological ulcer.Methods:This study is a prospective study,including 69 patients with DPN.We reference the VPT inspection results as DPN patients susceptible to neuropathic ulcer risk stratification basis,will dividing into three groups.Compare the general situation and indicators collected in three groups.Collect the clinical symptoms of patients and combine with tongue vein for syndrome differentiation.Refer to a literature mentioned DPN TCM syndrome types that form publishing in the journal of Chinese medicine,2011,called?Diabetes peripheral neuropathy of TCM prevention guide?.We use the spss21.0 statistical software to analyze the data,measurement data to((?)±s)said,comparison between groups using single factors variable variance analysis and count the percentage compared with x2 test data between the three groups,(P<0.05)indicating that the difference was statistically significant.Results:1.Low risk group,the moderate group,high-risk group general situation is :Compared with low risk group,high risk group,the moderate group age levels increased significantly(P<0.05),Compared with moderate group,high-risk groups of age level increased significantly(P<0.05);Comparison between groups,gender had no statistical significance(P<0.05);Comparison between each group,course of diseases had no statistical significance(P > 0.05).2.Low risk group,moderate and high-risk group blood sugar comparison: Compared with low risk group,moderate and high-risk group Hbl Ac levels were significantly higher(P < 0.05),compared with moderate group,high-risk groups Hbl Ac level increased significantly(P < 0.05);Compared with low risk group,reduced fasting blood glucose levels of high-risk groups,but the difference is not obvious,no statistical significance(P > 0.05),the rest of the group had no statistical significance(P > 0.05);Compared with low risk group,moderate and high-risk group Two hours after the meal blood glucose levels fall,two hours but no obvious difference with no statistical significance(P>0.05),and the rest of the group had no statistical significance(P > 0.05).3.Low risk group,the moderate group and high risk group of blood lipid comparison:Compared with low risk group,moderate and high-risk group triglyceride level increased significantly(P<0.05),compared with moderate group,high-risk group of triglyceride level increased significantly(P< 0.05).Low risk group,medium group,high-risk groups of low density lipoprotein cholesterol levels increased,but the difference is not obvious,there is no statistical significance(P > 0.05),the rest of the group of no statistical significance(P > 0.05);Compared with low risk group,high risk group of cholesterol was increased,but the difference is not obvious,no statistical significance(P > 0.05),the rest of the group had no statistical significance(P > 0.05).4.Low-risk group,the moderate and high-risk group of blood uric acid comparison:Compared with low risk group,high risk group,the moderate group blood uric acid levels were significantly higher(P < 0.05),compared with moderate group,high-risk groups of uric acid levels increased significantly(P < 0.05).5.Among 69 patients with DPN,TCM syndrome types in frequency from high to low order :Phlegm and blood stasis resistance 25 cases(36.2%),20 cases(29.0%)of the liver and kidney deficiency syndrome,Yin deficiency and blood stasis syndrome 15 cases(21.7%),qi deficiency and blood stasis 9 cases(13.1%).6.Four groups of syndrome types of age:Each group is age difference is not obvious,there were no statistical significance(P>0.05).7.Four groups of syndrome types of TG,Hbl Ac,blood uric acid :Compared with liver and kidney deficiency syndrome group,qi deficiency blood stasis,phlegm and blood stasis resistance collaterals syndrome of qi deficiency and blood stasis group blood uric acid levels were significantly decreased(P<0.05),no obvious difference is compared between the rest groups(P>0.05);Qi deficiency and blood stasis syndrome group,liver and kidney deficiency syndrome group triglyceride levels significantly decreased(P<0.05),the rest of the group triglyceride levels were decreased,but the difference is not obvious,no statistical significance(P > 0.05),Compared with phlegm and blood stasis resistance collaterals syndrome group,liver and kidney deficiency syndrome group triglyceride levels significantly decreased(P <0.05),the rest of the group had no statistical significance(P>0.05);there was no Hb Alc level to compare differences between groups,no statistical significance(P>0.05).Conclusion:1.Age,blood uric acid,TG,Hbl Ac is The influence factors of DPN patients with neuropathic ulcer risk degree;Phlegm and blood stasis resistance collaterals syndrome in patients with DPN accounted for the largest;Generally high Hbl Ac DPN patients of different syndrome types;DPN patients with kidney deficiency syndrome in patients with blood uric acid level is higher;DPN patients with qi deficiency and blood stasis syndrome,phlegm and blood stasis resistance winding patients triglyceride levels may be higher.