The Research On Diabetic Peripheral Neuropathy And Its Distribution Of Different Clinical Manifestations Of TCM Pathology

Objective:The syndrome factor differentiation method analysis of diabetic peripheral neuropathy and its different clinical manifestations, numbness, pain, the distribution characteristics of TCM pathology.Methods:This topic will be through the theoretical study and clinical research, using the method of syndrome factor differentiation, collecting352cases of patients with different clinical manifestations of DPN four diagnostic information, including1observation group195cases, observation2group157cases, and the use of statistical methods to analyze different clinical manifestations of DPN pathological distribution characteristics of TCM syndrome factor.Results:1. DPN clinical type numb as the main clinical manifestations of proportion is highest, at55.40%, followed by the pain as the main clinical manifestations, the proportion of44.60%.2. The common diseases of DPN syndrome factor distribution in the order:liver, kidney, spleen, lungs and heart.Common empirical disease resistance syndrome factor distribution in turn as follows:dampness, phlegm, heat, blood stasis.Common deficiency disease syndrome factor distribution, in order:Yin deficiency, blood deficiency, Yang deficiency, qi deficiency.3. Different gender of DPN syndrome factor:the distribution of disease syndrome factor in, on the frequency, different gender difference exists in the liver syndrome factor frequency distribution (P<0.05), the female liver syndrome factor high frequency than men.On integral, women than men are liver syndrome factor score also significantly higher (P<0.01).Sexual disease syndrome factor, on the frequency, the positive factor of dampness, phlegm in frequency has difference in gender (P<0.05), the female dampness, phlegm syndrome factor frequency are higher than men. On the integral, blood stasis syndrome factor score is significantly higher than men women (P<0.01).4. DPN TCM syndrome factor of pathologic distribution in different age groups:disease syndrome factor in, in terms of frequency, different ages in the liver and kidney syndrome factor, there exist some difference, frequency distribution among middle-aged group of liver syndrome factor is green, higher elderly group (P<0.05);In renal syndrome factor, in the elderly group than young group increased significantly (P<0.01);In terms of integral, different age difference exists in the renal syndrome factor score distribution, elderly group kidney syndrome factor rise in the youth, middle-aged group (P<0.05).Empirical syndrome factor, in terms of frequency, different age in wet, and qi stagnation syndrome factor, there exist some difference, frequency distribution of youth in the wet factor is rising, the elderly group (P<0.05);Middle-aged group and frequency is relatively young group increased (P<0.05).In terms of integral, in different ages and qi stagnation syndrome factor exists on the integral distribution difference, middle-aged group and qi stagnation syndrome factor is relatively young group increased (P<0.05).Deficiency syndrome factor, in terms of frequency, different age difference exists in the blood deficiency syndrome factor frequency distribution, relatively young, the elderly group blood deficiency syndrome factor of the elevated (P<0.05), in terms of integral, different age difference exists in the distribution of Yin deficiency syndrome factor, elderly group Yin deficiency syndrome factor increased significantly in the youth, middle-aged group (P<0.01).5. Gender, age, duration of the effect of each factor in the DPN:women relative to the possibility of a male blood deficiency, phlegm syndrome factor increased1.873and0.749times respectively.Age and kidney, Yin deficiency and Yang deficiency, blood deficiency syndrome factor positively correlated, the relationship between the OR values were1.982,2.081,1.256,1.134,1.749times.Course of the disease was positively correlated with Yang deficiency syndrome factor, OR a value of1.679times.6. Observation group and observed the pathological distribution of two groups of TCM syndrome factor:the observation group1empirical disease syndrome factor according to frequency of sex followed by wet> heat> sputum> blood stasis> qi stagnation, deficiency disease resistance syndrome factor according to the frequency of the Yin> blood deficiency> qi deficiency> Yang deficiency.Observe two groups empirical disease syndrome factor according to frequency of sex followed by wet> heat> phlegm> blood stasis> qi stagnation, deficiency disease resistance syndrome factor according to the frequency of the Yin> blood deficiency> Yang qi deficiency.In the two groups, in turn, are liver disease is a syndrome factor according to the frequency> kidney> spleen> heart> lungs.Two groups of frequency comparison, disease syndrome factor of phlegm, blood stasis syndrome factor frequency was statistically difference (P<0.05);Disease syndrome factor in renal syndrome factor frequency was statistically difference (P<0.05).Integral to compare the two groups, disease syndrome factor in Yin deficiency, blood deficiency syndrome factor was statistically difference (P<0.05);Disease syndrome factor of lung and kidney syndrome factor score was statistically difference (P<0.05).7. Observation group1, observe the risk factors of two groups:observation group1TCM pathology associated with liver, blood deficiency, phlegm, blood stasis (P<0.05), the OR value respectively (1.574,2.784,1.697,2.784).Observe two groups of TCM pathology associated with liver, Yang deficiency, phlegm and blood stasis (P<0.05), the OR value respectively (2.395,2.063,0.589,2.063).Results:1. DPN clinical manifestation to numb is relatively rare, followed by pain.2. Disease of DPN syndrome factor mainly in the liver, kidney, spleen, lung, heart, disease resistance syndrome factor mainly to Yin deficiency, qi deficiency and qi stagnation, heat, phlegm, dampness, blood deficiency, Yang deficiency, hand, blood stasis.3.Age, gender, duration of the influence of each factor:age affects the kidney, blood deficiency, Yin deficiency and Yang deficiency syndrome factor four changes. Gender affects the change of blood deficiency, phlegm syndrome factor, including women with blood deficiency, phlegm syndrome factor than men are more prominent. Course and Yang deficiency syndrome factor relations were positively correlated.4.The liver, blood deficiency, phlegm syndrome factor may be numb risk factors as the main clinical manifestations of DPN, liver, Yang deficiency, blood stasis syndrome factor may be risk factors of pain as the main clinical manifestations of DPN.