Application Of Compound Microporous Polysaccharide Haemostatic Powder In Total Knee Arthroplasty

Objective:This study aims to contrast patients using compound microporous polysaccharide haemostatic powder in total knee arthroplasty with patients who are not treated with compound microporous polysaccharide haemostatic powder in total knee arthroplasty and to figuer out the differences in postoperative 24 h drainage volume,postoperative 24 h hidden blood loss,postoperative 24 h total blood loss,surgical incision and deep vein thrombosis of lower limbs.This study aims to evaluate the efficacy and safety of the compound microporous polysaccharide haemostatic powder for the reduction of the blood loss in total knee arthroplasty.Methods:From September 2016 to November 2017 in Shanxi Dayi Hospital,patients who underwent unilateral total knee arthroplasty were selected as study subjects and divided into treatment group and control group through the random number table method and then do a prospective study.A total of 65 cases were collected,including 31 cases in treatment group and 34 cases in control group.In the treatment group,0.25 g compound microporous polysaccharide haemostatic powder was used as a hemostatic agent in addition to routine electrocoagulation during surgery.The hemostatic agent was sprayed on the bleeding sites of posterior articular capsule of the knee joint and other soft tissues.Electrocoagulation was only used in the control group.Then postoperative 24 h drainage volume,postoperative 24 h hidden blood loss,postoperative 24 h total blood loss,surgical incision and lower limb deep vein thrombosis were analyzed statistically.Results:The postoperative 24 h drainage volume(502.58±45.57 m L)and postoperative 24 h total blood loss(873.88±180.86 m L)in the treatment group are significantly lower than those in the control group(535.06 ± 71.24 m L;976.54 ± 189.40 m L)(P < 0.05).The postoperative 24 h hidden blood loss for the treatment group(301.00 ± 174.64 m L)is lower than that for the control group(360.95 ± 180.60 m L),but there is no significant difference(P > 0.05).There are no serious complications of incision infection and deep venous thrombosis of lower limbs during the follow-up period.Conclusion:The compound microporous polysaccharide haemostatic powder is effective in reducing the postoperative 24 h drainage volume and postoperative 24 h total blood loss after total knee arthroplasty.It is not effective for the reduction of the postoperative 24 h hidden blood loss.It does not increase the incidence of incisional infection and deep venous thrombosis of lower limbs.The application of the compound microporous polysaccharide haemostatic powder is effective and safe for the reduction of the blood loss in total knee arthroplasty.