| Objective: Xiao Ke eye disease is called Diabetic retinopathy in moedern society,which is one of the serious complications of diabetes,and also is one of the four leading causes of blindness in the world today.The purpose of this study is to retrospectively analyze the medical records of patients with diabetes mellitus,and study on the distribution characteristics of TCM Syndromes of Xiaoke eye disease,and its relationship with patients’ gender,age,course of disease,laboratory indexes,complications and other risk factors.Objective to investigate the etiology and pathogenesis of Xiao Ke eye disease,and provide evidence for its early prevention and treatment.Methods: Collect the related medical records of patients with Xiaoke eye disease from January 2016 to December 2016 in the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,and divid into two TCM Syndromes of yin deficiency and dryness-heat,deficiency of Qi and yin,deficiency of liver-yin and kidney-yin,syndrome of yang deficiency of spleen and kidney,yin-yang deficiency,blood stasis and phlegm stagnation,statistic to the patiens’ gender,age,course of disease,DR grade,blood lipid,blood pressure,creatinine,urea nitrogen and other related datas,and analyze the relationship between TCM syndrome type and Xiaoke eye disease.Resuilts: 1.The total number of samples of this study were 232 people.Distribution of DR in TCM Syndromes: syndrome of yin deficiency of liver and kidney,yin-yang deficiency,blood stasis and phlegm were the most,each accounted for 28.45%,28.02%,followed by two Yin deficiency of Qi and Yin,syndrome of yang deficiency of spleen and kidney accounted for 12.07%,syndrome of endogenous heat due to yin deficiency,accounted for 6.47%.2.There was a significant difference between the TCM Syndromes of DR and its classification,P<0.01.Compare with the syndrome of endogenous heat due to yin deficiency and other four syndromes,P<0.01.Compare with the yin-yang deficiency,blood stasis and phlegm and other syndromes,P<0.01.Compare the syndrome of yang deficiency of spleen and kidney with the yin-yang deficiency and blood stasis and phlegm,syndrome of deficiency of both qi and yin,P<0.01.3.Between the LDL of TCM syndromes of DR,difference have statistical sense,P<0.05.4.Through the comparison between the two types of TCM syndromes,between the liver and kidney yin deficiency syndrome with spleen and kidney yang deficiency,yin and yang deficiency,blood stasis syndrome in age difference was statistically significant,P<0.05.In the course of DR,there was statistical difference between the syndrome of endogenous heat due to yin deficiency,Qi and yin deficiency syndrome and liver kidney yin deficiency syndrome,P<0.05.There was difference between syndrome of yang deficiency of spleen and kidney and syndrome of deficiency of both qi and yin,syndrome of yin deficiency of liver and kidney,yin and yang deficiency,blood stasis syndrome in TC、LDL、Cr.Conclusion:1.Xiaoke eye disease is mixed with the actual situation,from the initial deficiency of yin develop to deficiency of both vital energy and yin,and finally to yin-yang deficiency.The deficiency of liver-yin and kidney-yin,spleen kidney yang deficiency,blood stasis and phlegm stagnation are important pathological changes in Xiaoke eye disease.2.The TCM syndrome type of DR was positively correlated with the classification,which indicated that with the development of DR pathogenesis,DR also developed from the NPDR to the PDR,and the disease aggravated.3.In this total statistics,the average FBG was 11.60mmol/L,the average Hb A1 c was7.60mmol/L,which was significantly higher than the normal value,pointed out that DR patients should still control blood sugar.4.In this study,there was difference between LDL of DR TCM Syndrome Types,the average value of LDL of each syndrome was higher than the normal value.In addition to the liver and kidney yin deficiency syndrome,the TG values of the other syndromes were higher than the normal value in TG.It is suggested that dyslipidemia is also a risk factor for the occurrence and development of DR. |