| Object:By comparing the correlation between blod biochemical indexes and symptom VAS score,and comparing the difference of incidence of low blood calcium and symptomatic hypocalcemia in SHPT patients after operation use two short-term calcium supplements.Compare the difference of the total hospitalization expenses,hospitalization time and the compliance of calcium supplementation.we can evaluate which method is more reasonable and effective,so as to guide clinical more effective calcium supplement.Methods:By collecting 36 cases of surgical treatment of gastrointestinal thyroid surgery in the First Affiliated Hospital of Shihezi University from February 2016 to December 2017,the clinical dates were Retrospective analysis.According to the different ways of calcium supplementation(1,2)were divided into two groups: A and B,18 cases in each group.Serum levels of parathyroid hormone,blood calcium and phosphorus in two groups of patients preoperative and 6h,1d,2d and 3d after the operation were checked,and the VAS scores of pain,itching and myasthenia symptoms preoperative and 1d,2d and 3d after operation were checked.The hospitalization expenses and hospitalization time of two groups of patients was counting.Comparing the correlation between the two groups preoperative and each time point of blood biochemical index,the symptom score of VAS after the operation.Compare the incidence rate between the two groups of postoperative short-term hypocalcemia and symptomatic hypocalcemia.Compared the total hospitalization expenses,hospitalization time and compliance of venous pump calcium between the two groups.We can summarize more effective preventive calcium supplementation.Results:(1)The levels of blood calcium,blood phosphorus and parathyroid hormone in the two groups of A and B in different time points before operation were significantly lower than those before the operation,and the difference was statistically significant(P<0.05).There was no significant difference in parathyroid hormone levels between the two groups at different time points after operation(P>0.05).The serum phosphate levels in group A was lower than that in group B at different time points after operation.The serum phosphate levels of the two groups showed a decreasing trend,and there was no significant difference in the trend of change between the two groups(P>0.05).The blood calcium level of different time points after operation in group B was significantly lower than that in group A(P<0.01).Short term after operation,there were 2 cases of hypocalcemia in group A(11.1%),and 9 cases of hypocalcemia in group B(50%),and the incidence of hypocalcemia in group A was significantly lower than that in group B(P<0.05).After operation,there were 0 cases of symptomatic hypocalcemia in the short-term A group(0%),3 cases of symptomatic hypocalcemia in group B(16.7%),and no significant difference in the incidence of symptomatic hypocalcemia in the two groups(P>0.05).(2)A,B two groups of bone pain,itching symptoms,myasthenia VAS score in different time points were significantly lower than before the operation,the difference was statistically significant(P<0.001),twogroups of postoperative bone pain,itching symptoms,myasthenia VAS score showed a decline trend,the change trend difference was not statistically significant(P>0.05).There was no significant difference between the two groups in the VAS scores of pruritus and myasthenia in different time points(P>0.05).The VAS score of pain in group A was significantly lower than that in group B in postoperative1D(P<0.01).There was no significant difference between the two groups in the VAS scores of pain in postoperative 2D and 3D(P>0.05).(3)The hospitalization expenses and hospitalization time of group A were significantly lower than those of group B(P<0.05).Intravenous calcium pump of A group of in higher compliance rate was significantly lower than in group B(P<0.05)Conclusion:(1)In the short term after operation,the preventive calcium supplementation 1 could more effectively prevent the occurrence of hypocalcemia,and the two preventive calcium supplementation can make the incidence of symptomatic hypocalcemia was all low.(2)The short-term bone pain,pruritus and myasthenia after two preventive calcium supplementation were improved effectively,and the effect of bone pain symptoms more improved in the short term of preventive calcium supplement 1.(3)The preventive calcium supplementation mode 2 is lower than the way 1 in total hospitalization expenses and hospitalization time,and is also superior to mode 1 in the compliance of venous pump calcium. |
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