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The Clinical Value Of Cone-Beam Computed Tomography Parenchyma Blood Volume(CBCT-PBV) In The Treatment Of TACE For Hepatocellular Carcinoma

Posted on:2019-04-23Degree:MasterType:Thesis
Country:ChinaCandidate:J F LiFull Text:PDF
GTID:2394330566970661Subject:Imaging and nuclear medicine
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Objects: Preliminarily exploring the clinical value of the CBCT-PBV in the treatment of TACE for hepatocellular carcinoma.Methods: Patients with liver cancer treated with TACE in our interventional ward were collected from March 2017.All patients were examined with enhanced CT or Mr of liver before operation,and general data and blood biochemical indexes were collected.Patients who met the criteria of case entry were included in the study.Two groups of data were tested by t test.The analysis of variance was used in the comparison between different groups.The Bland-Altman consistency analysis was performed on the measurement results of intrahepatic focus and lesion size by different examination methods.According to m RECIST criterion,they were divided into two groups: OR and SD/PD.The counting data of two groups were analyzed by t test.The Kappa test showed that the difference was statistically significant(P < 0.05).Results: A total of 28 cases were collected from March 2017 to June 2017,including 16 males and 12 females.The largest intrahepatic lesion in each patient was selected as the research object,and 28 of them were included in this study.The Bland-Altman plot showed good agreement about the size of lesions between preoperative imaging examination(3.07cm±1.00cm)and preoperative PBV images(3.16cm±1.07cm).The dose of lipiodol for embolization existed correlation with the value of K(r = 0.56,P <0.05).The prognosis of the patients was divided into OR group and SD/PD group.The proportion of residual perfusion in OR group was lower than that in SD/PD group(P <0.05).Conclusions: The CBCT-PBV technique which was accurate and reliable and provided the quantitative assessment for intraoperative embolization and the prognosis has a great importance clinical value.
Keywords/Search Tags:Cone-Beam computed tomography(CBCT), Parenchyma blood volume(PBV), Hepatocellular carcinoma(HCC), TACE
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