The Relationship Between Admission Neutrophil-to-Lymphocyte Ratio,Lymphocyte-to-Monocyte Ratio And Short-term Outcome In Acute Intracerebral Hemorrhage

Objective:To explore the association between the neutrophil-to-lymphocyte ratio(NLR)and lymphocyte-to-monocyte ratio(LMR)and short-term outcome of acute intracerebral hemorrhage.Methods: The observational study included 177 patients with acute intracerebral hemorrhage.The clinical data,radiologic characteristics and blood test were documented on admission.NLR and LMR were calculated by ANC,ALC and AMC.Patients were divided into two groups depended on m RS at 90 th days after onset.The association between information and ICH outcome was investigated with single factor analysis.Logistic regression analysis was used to adjust possible confounders.The receiver operating characteristic curve was used to evaluate the effect of the indicators above on short-term outcome of acute intracerebral hemorrhage.Results:One hundred seventy-seven subjects were enrolled.Sixty-eight had unfavorable outcome.WBC,ANC,ALC,NLR,LMR,blood sugar on admission and surgical treatment,NIHSS score and GCS score were significantly statistical different between two groups(p < 0.05),while there was no significant difference in AMC(P=0.115).The LMR and NLR were independently associated with the 3-monthstatus[OR(95%CI)were3.675(1.616~8.358),2.522(1.159~5.491)respectively;all P<0.05].The area under curve of NLR and LMR were 0.779 and 0.710.And the best predictive cut-off value of NLR was 5.63.The best predictive cut-off value of LMR was 2.93.Conclusions:In patients with acute intracerebral hemorrhage,higher NLR and lower LMR may independently predicted worse short-term outcome.