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Investigation Of Protein And Phosphorus Intake In Patients With Chronic Kidney Disease And Evaluation Of Maroni And Boaz Formula

Posted on:2019-01-17Degree:MasterType:Thesis
Country:ChinaCandidate:Y W ZhangFull Text:PDF
GTID:2394330566970387Subject:Public Health
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Objective:To evaluate the actual dietary protein and phosphorus intake in patients with CKD in China from 3 to 5 and 5D.To explore whether the Boaz formula can reflect the true phosphorus intake China CKD patients.Whether the Maroni formula can accurately predict the protein intake of patients before CKD3-5 dialysis.Methods:Selected inpatients in the Department of Renal Medicine,the first affiliated Hospital of China Medical University,the CKD-EPI formula was used to calculate the glomerular filtration rate in order to judge the renal function of the patients110 in patients with eGFR?60 ml/min 1.73 m2 were selected to meet the criteria of inclusion and exclusion.According to the K/DOQI guidelines,the patients were divided into four layers according to eGFR.All patients received standard nephropathy treatment and nutritional health education.Nutritional risk screening was carried out in patients with CKD.Dietary intake(weighing method)and dietary habits were investigated and biochemical indexes were collected.The actual intake of protein and phosphorus was calculated by using the computer expert system of nutrition combination of traditional Chinese and western medicine,and the statistical description and analysis were carried out by SPSS20.0.Results:1.In nutritional risk screening,the incidence of nutritional risk in CKD3-5D patients was 35.7%,42.3%,60.7%,64.3%respectively,and 58.9%in females)was higher than that in males(41.1%).2.The actual intake of protein in phase CKD3-5 patients gradually decreased and met the recommended intake;the actual intake of protein in phase CKD5D increased,but was lower than the recommended intake.3.Compared with the recommended intake,the actual intake of phosphorus in the patients in stages 3-4 and5D was within the standard range,but in the fifth period was lower than the level below the level of eligible intake.There was a positive linear correlation between protein intake and actual phosphorus intake in CKD patients R~2=0.83,r=0.91(p<0.01).5.The factors affecting the actual intake of protein and phosphorus in CKD patients,the actual intake of phosphorus,and drinking may be the factors affecting the actual dietary protein intake(p<0.05).The actual protein intake and BMI may be the factors affecting the actual dietary phosphorus intake(p<0.05).6.During the study period,there was no significant difference in protein intake,albumin,serum creatinine,blood uric acid,blood urea nitrogen,blood phosphorus and other biochemical indexes(p>0.05),and there was a statistically significant difference between the protein intake and prealbumin(p<0.05).There was no significant difference between actual phosphorus intake and serum albumin,prealbumin,serum creatinine,serum uric acid,blood urea nitrogen,blood phosphorus and other biochemical indexes(p>0.05).7?Protein intake was evaluated by maroni formula and compared with actual intake.There was significant difference between the actual intake of protein and the estimated intake in CKD3-5 patients(p<0.05).Phosphorus intake was evaluated by Boaz formula and compared with actual intake.There was no significant difference between the actual intake of phosphorus and the estimated intake in CKD3-5D patients(p>0.05).Conclusions:1.There is a high risk of malnutrition in patients with end-stage nephropathy,suggesting that it is necessary to take individualized nutrition management measures to improve nutritional status.2.Most CKD patients can reasonably control their diet according to the recommended amount of guidelines,so dietitians should strengthen nutrition education and improve compliance.3.The intake of protein and phosphorus in CKD patients was influenced by dietary habits,body shape and other factors.4.Maroni formula is not suitable for evaluating the actual intake of protein in CKD patients in China,but Boaz formula is suitable for evaluating the actual intake of phosphorus in CKD patients in China.
Keywords/Search Tags:chronic kidney disease, dietary protein, dietary phosphorus, Maroni formula, Boaz formula
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