Clinical Analysis Of Risk Factors For Early Acute Lung Injury After Liver Transplantation

Objective:The related risk factors of acute lung injury(ALI)were analyzed in the early stage of adult orthotopic liver transplantation.Therefore,it is more timely and accurate to provide the basis for clinical prevention and treatment of lung injury.Method : Retrospective analysis of the clinical data of donor recipients of liver transplantation from January 2006 to October 2016.All the liver is for the liver.A total of 139 cases were included in the study following the exclusion criteria,and lung injury occurred in the early stage of liver transplantation.The patients were divided into acute lung injury group(ALI)and non-acute lung injury group(NALI),To compare two groups of donor and recipient preoperative,intraoperative and postoperative observation indexes.and the two groups were compared before,during and after surgery.Multifactor Logistic regression analysis was used to explore the factors influencing acute lung injury in patients with liver transplantation.Results:Acute lung injury occurred in 44 of 139 cases of liver transplantation,with an incidence of 31.65 %.Single factor Logistic analysis showed donor preoperative presence of fatty liver(P = 0.005),receptorsage(P = 0.017),receptors preoperative total bilirubin level(P = 0.03),intraoperative blood loss(P = 0.017),red blood cells transfused(P = 0.001),amount of plasma transfused during surgery(P = 0.007)and length of time of surgery(P = 0.004)differences statistically significant(P <0.05).Multiariable Logistic analysis showed donor preoperative presence of fatty liver(P = 0.015,OR = 0.015,confidence interval 0.005 to 0.853),the recipient age(P =0.027,OR = 0.027,confidence interval 1.008 to 1.142),receptor preoperative total bilirubin level(P = 0.003,OR = 0.03,confidence interval 1.003 to 1.009)are independent risk factors for acute lung injury after liver transplantation.high risk factors of the postoperative acute lung injury(P < 0.05).Conclusion:For donor fatty liver,liver transplant receptor age,receptors preoperative total bilirubin levels are independent risk factors for acute lung injury after liver transplantation.and to predict postoperative liver transplantation can provide clinical reference acute lung injury.