Correlative Analysis Of Low Body Mass Index And Severity Of Coronary Artery Disease

Objective:To explore the possible influence of low BMI on the severity of coronary artery disease,and to provide new ideas for the prevention and treatment of low BMI coronary heart disease.Methods:The inclusion target excludes exclusion criteria such as prior revascularization and total 632 cases that meet the inclusion criteria.According to the body mass index,they were divided into three groups:low BMI group(BMI<20 kg/m~2,44 cases),normal BMI group(20 kg/m~2?BMI<25 kg/m~2,302 cases),and high BMI group(BMI?25kg/m~2,286 cases).The general clinical data,blood biochemical indicators,and SYNTAX scores were collected among the 3 groups.The relationship between BMI subgroups and SYNTAX scores was analyzed using analysis of variance,multiple-rank rank sum test,chi-square test with multiple sample rates,and Logistic regression.Results:1.In the general clinical data,women in the low body mass index group had the highest proportion,and women in the high body mass index group had the lowest proportion.The median age of patients with high BMI was lower than those with low BMI and normal BMI.There was a statistically significant difference in sex and age between the 3 groups,P<0.05.2.Serum biomarkers:Low body mass index group had the lowest levels of prealbumin,serum triglycerides,serum total cholesterol,and serum high-density lipoprotein cholesterol.The body mass index group is the opposite.There were significant differences in the levels of prealbumin,serum triglycerides,serum total cholesterol,and serum high-density lipoprotein cholesterol between the 3 groups,P<0.05.3.There was no statistical difference in the left ventricular ejection fraction between the 3 groups.significance.In group 4 and group 3,in the distribution of high scores in SYNTAX scores,patients with high scores in the low body mass index SYNTAX score had the highest ratio,and normal body mass index group had the lowest ratio,with statistical significance between the groups,P=0.05.In the BMI group as a control group,logistic regression analysis showed that the risk of high scores in the SYNTAX score was significantly higher in the low BMI and high BMI groups than in the normal BMI(OR:3.109,95%CI 1.494-6.065;OR:1.539,95%).CI1.037-2.285)).After adjusting for age,gender,smoking history,drinking history,hypertension,diabetes,concomitant diseases,prealbumin,triglycerides,high-density lipoprotein cholesterol,and total cholesterol,the difference was still statistically significant.Logistic regression analysis using high BMI as a positive control group and low BMI suggested that the high BMI was higher than the high BMI in the SYNTAX score(OR:2.020,95%CI(1.047-3.897)).After adjusting for age,gender,smoking history,drinking history,hypertension,diabetes,concomitant diseases,prealbumin,triglycerides,high-density lipoprotein cholesterol,and total cholesterol,the difference was still statistically significant.Conclusion:Patients with low body mass index had a higher SYNTAX score than patients with normal body mass index and high body mass index,and had more serious coronary artery disease.