The Effectiveness And Safety Of Sleeve Gastrectomy In The Obese Elderly Patients: A Systenmatic Review And Meta-analysis

Objectives:The effectiveness and safety of sleeve gastrectomy(SG)in the old population are still disputable.This systematic review was performed to compare the effectiveness and safety of SG in the obese elderly patients with the young ones.Methods:We searched the electronic databases PubMed,the Cochrane Library and Embase for literature published.Studies focusing on outcomes of old and young patients who had undergone SG were included.Standard mean differences(SMDs)and risk ratios(ORs)were calculated on pooled effects.Results:11 publications were concluded.A total of 2250 patients who had undergone SG,among them 413 were old patients,while 1837 were young ones.Old patients had a worse outcome in percentage of excess weight loss(EWL%)than the young ones(SMD-0.39,95%CI-0.55 to-0.24).No significant differences were recorded in resolution of co-morbidities:type 2 diabetes mellitus(T2DM)(OR 1.60,95%CI 0.84-3.05),hypertension(OR 1.05,95%CI 0.65-1.68),dyslipidemia(OR 1.38,95%CI 0.68-2.80),obstructive sleep apnea hypopnea syndrome(OSAHS)(OR 0.64,95%CI 0.30-1.34),or postoperative complications(OR 0.89,95%CI 0.51-1.55)between the elderly and the young who had undergone SG.Conclusions:SG was effective for weight loss and resolution of co-morbidities with low complication rate in the obese elderly patients.