Font Size: a A A

Analysis Of Clinical Features Of Nonalcoholic Fatty Liver Disease

Posted on:2019-06-24Degree:MasterType:Thesis
Country:ChinaCandidate:X F ZhaoFull Text:PDF
GTID:2394330548994684Subject:General medicine
Abstract/Summary:PDF Full Text Request
Objective:By analyzing the clinical information of inpatients with non-alcoholic fatty liver disease(NAFLD)and inpatients of non-NAFLD,we explored the predisposing factors and clinical features of NAFLD,raised awareness of the disease,and obtained early diagnosis and treatment for it.Providing an theoretical basis.Methods:Transient elastography(TE)was used to screen patients admitted to the Department of Geriatric Gastroenterology at the First Affiliated Hospital of Kunming Medical University from November 2016 to December 2017.A total of 356 NAFLD inpatients were collected(200 males and 156 females).There were 404 cases non-NAFLD inpatients(230 males and 174 females)with a total of 760 cases.Retrospective analysis of gender,age,CAP,LSE,body mass index(BMI),serum triglyceride(TG),serum high-density lipoprotein cholesterol(HDL-C),serum low-density lipoprotein cholesterol(LDL-C),blood Uric acid(SUA),with or without hypertension and abnormal glucose metabolism.SPSS 22.0 was used for statistical analysis,and t-test,one-way analysis of variance,chi-square test,and linear correlation analysis were used to statistically analyze the prevalence of NAFLD in this group.Results:1.The BMI,LSM,TG,LDL-C,fasting glucose and SUA in NAFLD group were higher than those in non-NAFLD group.The HDL-C in NAFLD group was lower than that in non-NAFLD group.The prevalence of hyperglycemia was higher in the NAFLD group than in the non-NAFLD group.Statistically significant(P<0.05).2.Obesity,hyperglycemia,hypertriglyceridemia,low HDL-C hyperlipidemia,and HUA prevalence differed among patients with different degrees of hepatitis steatosis:The higher the degree of steatosis,the higher the prevalence of abnormal metabolic conditions(P<0.05).3.There was a positive correlation between the liver fat index CAP and the number of MetS components(P<0.05).4.The LSE of the NAFLD group was higher than that of the non-NAFLD group(P<0.05).Conclusions:Patients with NAFLD can be screened early by measuring ergonomic parameters(height,weight,waist circumference,etc.),blood biochemistry,CAP,and LSE.Any presence of metabolic components(obesity,hypertension,hyperglycemia,hypertriglyceridemia,and low HDL-C hyperlipidemia)in hospitalized patients should be promptly followed by CAP and LSE to determine whether there is NAFLD.Patients with NAFLD should be screened one by one for each metabolic component The LSE value of NAFLD patients in this group was higher than that of the normal population.LSE should be monitored regularly and related treatment should be performed in time to avoid the occurrence of advanced liver fibrosis.
Keywords/Search Tags:Nonalcoholic fatty liver disease, transient elastography, clinical features
PDF Full Text Request
Related items