The Investigatation On Applicationg Time Of Carboprost Tromethamine In Placental Abruption Result In Postpartum Hemorrhage

Objective:Combined with clinical practice experience,To carry out the investigatation on application Time of Carboprost Tromethamine in Placental abruption result in postpartum hemorrhage,the study provide reference for clinical diagnosis and treatmeng.Method: To select 68 in the patients of Ⅱ degree of placental abruption result in postpartum hemorrhage for the study object during January 2014 to June 2017.68 of diagnosis and treatment of the patients,through the comprehensive analysis,collecting,sorting and summarizing carried out,At the same time,to use mcrosoft excel establish a database,statistical analysis was performed using SPSS17.0 statistical software.divided into two groups: two groups were injected with oxtocin 20 U in uterine muscle after delivery of fetus,and at the same time,oxtocin 10 U was added to the 500 ml glucose intravenous drip.Group A was were injected with Carboprost Tromethamine 0.25 mg in uterine muscle after delivery of fetus;In group B,the uterine body muscle was were injected with Carboprost Tromethamine 0.25 mg after delivery of fetus and hemostasis failed.To observe and record intraoperative bleeding time、2 hours of bleeding、24 hours of bleeding、the treatment effect 、the adverse event rate.Result:1.There was no significant difference between the two groups in general situation and gestational weeks of puerpera of Ⅱ degree placental abruption result in postpartum hemorrhage(P>0.05).2.There was no significant difference between the two groups in predisposing factors of puerpera of Ⅱ degree placental abruption result in postpartum hemorrhage(P>0.05).3.There was no significant difference between the two groups in fatal weight<2500g、premature infants、stillbirth、transferred from pediatric department、perinaltal mortality of Ⅱ degree placental abruption result in postpartum hemorrhage(P>0.05).4.Compared the two groups,it was found that postpartum bleeding time of group B was significantly longer than that of group A,and the 2 hours、24 hours bleeding volume of group A was significantly lower than that of group B,the difference was statistically significant(P<0.05).5.The carboprost tromethamine of A group repeatedly high total effective rate significantly higher than that of group B after injection,the difference was statistically significant(P<0.05).6.The adverse event rate of A group repeatedly lower than that of group B,the difference was statistically significant(P<0.05).Conclusion:1.Ⅱ degree placental abruption result in postpartum hemorrhage for the women,on the carboprost tromethamine medication time shall be used as early as possible in the earlypostpartum hemorrhage,at the same time consider the postpartum hemorrhage rate.2.Ⅱ degree placental abruption result in postpartum hemorrhage for the prevention of the women application carboprost tromethamine can achieve the best effect,at the same time can aviod unnecessary hysterectomy.3.Ⅱ degree placental abruption result in postpartum hemorrhage for the prevention of the women application carboprost tromethamine can consider the adverse event rate.