| Contemporary society,science and technology rapid development,gradually improve urban industrialization,but also brought great disadvantages for people’s life,due to the pollution of environment,all kinds of respiratory disease,lung disease,become the city high incidence of disease,cough and gasp the which is the main representation of lungs and respiratory diseases,cough and gasp the characterization of the common similar respiratory infections,bronchitis,pneumonia,these diseases.Due to the complex etiology of cough and asthma,the disease is not single and often is the manifestation of comprehensive diseases.Therefore,the Chinese medicine has a great advantage over western medicine.Comprehensive consideration of the characteristics of the medicinal materials and the ease of use of the drug,the change of the compound decoction to the capsule is so much improved the ease and convenience of drug use.His own by kidney runfei,fundamentally treatment to cough and gasp the,ha out oil from the seeds invigorating the toad jing,Yin runfei,for your medicine,fruit of Chinese magnoliavine acidity of the product,the folding of the lung cough,zi kidney,prevent lung Yin qi dissipation,ginseng tonic lung qi.Orange pedicle to stop cough and phlegm,the drug is loaded into the lung,the combination of drugs,invigorating lung kidney,the treatment of lung and kidney deficiency cough and asthma.Due to the rich protein,fat and volatile animal drugs,the effect can be reduced through ethanol extraction.So in order to preserve its efficacy and activity,directly crush the mixture to join.Design L16(4~5)orthogonal test,the measured content of ginseng total saponin on the basis of measurement standard,comprehensive extract rate,the best extraction conditions,60%ethanol concentration,six times the amount of solvent,the extraction of 3 h,under the condition of 70 degree,extract twice.Income of dry extract powder and the toad seed mix points out oil mixture,add accessories,for the drug utilization rate of effective component content and reasons,ha out oil from the seeds,toad directly crush medicine,dry paste powder mixed with extract gains,because of which is cream powder and the toad out oil seed mix cent,have hygroscopicity,should first join the supplementary materials to reduce its hygroscopicity,measuring its hygroscopicity and liquidity to draw materials,the screening of the drying temperature and time,to control the moisture within the scope of qualified,in measuring the mixing uniformity,prevent its blending,lump phenomena exist,filling in capsules.The content of the quality standard of harshen capsule was the TLC identification of ginseng,fructus schisandrae and platycodon.For three kinds of ginseng saponins in ginseng inspection standards,establishing quality methodology research,using HPLC method for determination of content and its methodology,investigation projects include:linearity,specificity,repeatability,stability and recovery,intermediate precision.The results show that the method is good and sensitive,and the indexes meet the pharmacopoeia standard,which can be used as the quality standard.Capsule to carry on the preliminary stability test of ha,according to the light,high temperature,high humidity and other factors on the preparation,the effects of experimental results,the initial stability study ginseng capsules,by testing factors,moisture,disintegration time limit,the main content,came to the conclusion that each project all qualified.Through the result of the experiment factors were analyzed,and the conclusion is obtained and ha ha out of ginseng capsules containing oil,toad seed,naphtha,etc.,with the physical properties and chemical properties will still be relatively influence on its preservation and storage.Try to choose the good conditions of low temperature drying and avoiding light for preservation. |
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