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Evaluation Of Left Ventricular Systolic Function After PCI Operation In Patients With Coronary Artery Disease By Three-Dimensional Speckle Tracking Imaging

Posted on:2019-12-22Degree:MasterType:Thesis
Country:ChinaCandidate:L ZhangFull Text:PDF
GTID:2394330548956304Subject:Imaging and nuclear medicine
Abstract/Summary:PDF Full Text Request
Objective: The application of three-dimensional speckle tracking imaging(3D-STI)technology to assessment the changes of left ventricular systolic function and synchronization before and after percutaneous coronary intervention(PCI)in patients with coronary heart disease,to analyze the short-term effect of PCI on the reperfusion of coronary heart disease,and to evaluate the value of 3D-STI in the evaluation of the effect of PCI on the patients with coronary artery disease.Methods: 65 subjects were stratified based on coronary angiography(CAG)imaging,comprising 23 patients with single-vessel CAD,and 41 controls.All patients underwent two-dimensional and three-dimensional echocardiography before the procedure,one month after the procedure and three month after the procedure,collect and store three dimensional full volume images,after being off-line,the 3D-STE is used to analyze the stored images.left ventricular myocardial global strain parameters and systolic peak strain of 17 segments were automatically measured,the parameters of left ventricular systolic synchrony were calculated.Results:1.Compared with the control group,there was no significant difference in the basic clinical data of CHD group,but LVEDV and LVESV were expanded(P <0.05),LVEF was reduced(P <0.05);in CHD group,when one month after the procedure and three month after the procedure,LVEDV,LVESV and LVEF have obviously changed than pre procedure(P < 0.05);compared with one month after the procedure,when three month after the procedure,LVEDV and LVESV had a certain reduction(P < 0.05)and LVEF increased(P < 0.05).2.compared with the control group,left ventricular myocardial global strain parameters of CHD group were all decreased(P <0.05);in CHD group,when one month after the procedure and three month after the procedure,the parameters increased than preprocedure,and significantly higher after three month of the procedure(P < 0.05);Receiver operating characteristic curve(ROC)analysis showed thatthe area under the curve(AUC)of GLS and GAS was between 0.70-0.90,therefore,both of them evaluated the improvement of left ventricular systolic function accurately,the sensitivity was 85% and 78%,and the specificity was 67% and 89%.3.compared with the control group,the parameters of left ventricular systolic synchrony of CHD group were all increased(P <0.05);in CHD group,when one month after the procedure and three month after the procedure,the parameters decreased than preprocedure,and decreased more significantly after three month of the procedure(P < 0.05).Conclusion: 3D-STI has certain value in evaluating left ventricular systolic function and synchronization in patients with coronary artery disease,the parameters of longitudinal strain and area strain are more sensitive reference indexes.
Keywords/Search Tags:three-dimensional speckle tracking imaging, Coronary artery disease, left ventricular systolic function and synchronization
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