Analysis Of Distribution And Drug Resistant Of Pathogens In Patients With Stoke-associated Pneumonia In ICU Of Neurology Department

Objective To investigate distribution and characteristics of antibiotic resistance of sputum pathogens for stroke-associated pneumonia(SAP)in ICU of neurology department to provide the reference for early clinical treatment.Methods The clinical data of 225 SAP patients in ICU of neurology department in our hospital from Jan.2012 to Jan.2017 were reviewed.The distribution and antibiotic sensitivity of pathogens isolated from the cultured sputum collected from the patients were analyzed.Results 115 cases were positive for sputum,The positive rate was 51.1 %,a total of 115 strains of pathogens were isolated including 137 strains(69.2%)of gram-negative bacteria,41 strains(20.7%)of gram-positive bacteria and 20 strains(10.1%)of fungi.Gram-negative bacteria had the lowest drug resistance rate to imipenem,meropenem and amikacin,followed by piperacillin / tazobactam and cefoperazone / sulbactam,and common resistance to ceftriaxone,ceftazidime,cefepime,ciprofloxacin and gentamicin;gram-positive bacteria had the lowest resistance rate to tigecycline,vancomycin,linezolid,the resistance rate of Rifampicin,penicillin,erythromycin and ciprofloxacin was the highest,and the resistance rate was 100 %,fungi were generally highly sensitive to common antifungal drugs.Conclusions In the patients with SAP in ICU of neurology department,gram-negative bacteria is the main pathogen,the common antibiotic resistance is common,and some of them are multi-drug resistance.clinical doctors should take bacterial culture and drug sensitivity test several times as early as possible.according to the distribution characteristics and drug resistance of the pathogens,antibiotics should be selected rationally.