| Objective: To investigate the effect of combined type 2 diabetes on lymph node metastasis of thyroid papillary carcinoma.Methods: The clinical data of 300 cases of thyroid papillary carcinoma treated by thyroid surgery in the second affiliated hospital of Da Lian medical university from June2015 to June 2017 were retrospectively analyzed,analysis of type 2 diabetes of lymph node metastasis in patients with thyroid papillary carcinoma.In all cases,the surgeon performed the lateral thyroid gland resection of the patient with lateral adenotomy and the central group lymph node dissection,and the thyroid isthmus was excised together.Bilateral thyroid carcinoma underwent total thyroidectomy with bilateral central group lymph node dissection,and unilateral(or bilateral)functional cervical lymph node dissection was performed in the combined lateral lymph node metastasis.According to whether patients with diabetes,age,men and women,whether primary tumor diameter,capsular invasion,preoperative serum TSH concentrations and multifocal tumor to compare two groups of patients and the overall sample.Results: The lymph node metastasis rate in the type 2 diabetes group and the control group was different,and the lymph node metastasis rate in the type 2 diabetes group was greater than that in the control group,P < 0.05.The lymph node metastasis of > 1cm and ?1cm in tumor diameter was different,and the lymph node metastasis rate of > 1cm was larger than that of tumor diameter of ?1cm,P < 0.05.There was a difference in lymph node metastasis between the age of< 45 and? 45 years old,and the rate of lymph node metastasis under 45 was greater than that of ? 45 years old,P< 0.05.Multiple focal lymph node metastasis rates were different from those of non-multifocal lymph node metastasis,and multiple focal lymph node metastasis rate was greater than that of non-multifocal lymph node metastasis,P < 0.05.There was no difference in the lymph node metastasis between ?2.5miu/l and > 2.5miu/l,P >0.05.Thyroid capsular invasion and lymph node metastasis rate between thyroid capsular no violations,thyroid capsular invasion of lymph node metastasis rate is greater than the envelope without lymph node metastasis rate of the infringement,P <0.05.There was a difference in lymph node metastasis between men and women,and the rate of lymph node metastasis in men was greater than that in women,P < 0.05.Finally,type 2 diabetes,gender,serum TSH concentrations,tumor multifocal,age,tumor diameter and capsular invasion of logistic regression analysis showed that diabetes is a risk factor for thyroid papillary carcinoma,lymph node metastasis.Conclusion:Type 2 diabetes is a risk factor for cervical lymph node metastasis in thyroid papillary carcinoma. |
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