The Clinical Study On The Maggot Debridement Therapy In The Diabetic Foot Ulcer Syndrome Of Damp-heat And Toxin Accumulation Type

Objective:To observe the clinical effect of maggot debridement therapy on the diabetic foot ulcer syndrome of Damp-heat and Toxin Accumulation Type and to provide valuable reference for the treatment of diabetic foot.Methods:From December 2015 to December 2017,in the First Affiliated Hospital of Dalian Medical University,endocrinology,vascular surgery,orthopaedics hospital and clinics and the Fourth People's Hospital of Dalian endocrinology,wound repair inpatient and outpatient with the diabetic foot ulcer syndrome of Damp-heat and Toxin Accumulation Type,for patients included in the sample,sign the informed consent,and to explain to the patient and relative to this topic in detail again treatment process,to ensure that patients know and understand the treatment plan.This subject collected a total of 42 patients who fully met the inclusion criteria for the type of diabetic foot ulcer.Adopt a random number table to group.21 patients were randomly divided into treatment group and 21 patients in the control group.The patients in the treatment group were treated with maggot biological debridement,and the patients in the control group were treated with conventional dressing and the treatment period was 30 days.During treatment by observing and detailed records culture turn time of patients with ulcer wound secretion,with a digital camera and a transparent membrane and photo shop software to record changes in patients with wounds include: area,the depth of the wound,granulation tissue,pus,swelling and pain in patients with a weeks changes such as changes in clinical symptoms,such as record total integral syndrome before and after the treatment,the SPSS20.0 statistical software to analyze data,to contrast the treatment efficacy of two groups of samples.The reduction rate of wound surface area was calculated and the efficacy of the two groups of samples was compared.Results: 1)there were 40 patients in the clinical study,20 in the treatment group and20 in the control group.General information: there was no statistically significant difference between the male and female components of the treatment group(P> 0.05).There was no significant difference in age distribution between the treatment group and the control group(P>0.05).The total effective rate of the treatment group was 80%.The total effective rate was 65% in the control group.The reduction rate of wound area in the treatment group was larger than that of the control group,and the difference betweenthe two groups was statistically significant(P<0.05).The wound depth score of the treatment group was less than that in the control group,and the difference between the two groups was statistically significant(P<0.05).The growth recovery of granulation tissue in the treatment group was less than that of the control group,and the difference between the two groups was statistically significant(P<0.05).The time to bacterial negativity of the maggot debridement treatment group is less than that of the conventional treatment group and the difference between the two groups was statistically significant(P<0.05).In the treatment group,the change of the wound abscess in the treatment group was less than that in the control group,and the difference between the two groups was statistically significant(P<0.05).In the treatment group,the score of the lesion was less than that of the control group,and the difference was statistically significant(P<0.05).The pain change score of the treatment group was less than that of the control group,and the difference between the two groups was statistically significant(P<0.05).Conclusion : The treatment effect of Maggot debridement therapy on diabetic foot ulcers in syndrome of Damp-heat and Toxin Accumulation Type is superior to that of conventional medicine.