The Effect Of Aflatoxin B₁ On The Growth Performance Of Broilers And The Use Effect Of Demildew Agents Were Evaluated

This exPeriment was aimed to investigate the effects of different levels of Aflatoxin B₁?AFB₁?and different tyPes of mycotoxin adsorbent aPPlied in AFBI contaminated diet on growth Performance in broiler.A high AFB₁ contaminated corn with different ProPortions substituted for normal corn?low level of AFB₁?in the exPerimental diets.The effect of mycotoxin adsorbent was added in the high level of AFB₁ diet on growth Performance,live biochemical indices and anti-oxidation activity was also investigated.In exPeriment 1,dwarf yellow feathered male chickens were chosen to divided into five treatments with seven rePlicates of seventy five each.Diet in treatment 1 was low AFB₁ level?1.32?g/kg?.Levels of AFB₁ in diets form treatment 2⁴ were 19.33?g/kg?51.77?g/kg?99.36?g/kg,resPectively.Levels of AFB₁ diets in treatment 5 in the starter?day 1-21?and grower?after day 21?Phase were 0.53?g/kg and 53.60?g/kg.In ex Periment 2,dwarf yellow feathered male chickens were chosen to divided into six treatments with six rePlicates of seventy five each.Diet in treatment 1 was low AFB₁ level?1.24?g/kg?.Diet in treatment 2 was high AFB₁level?45.44?g/kg?.Levels of AFB₁ in treatment 3⁶ were 41.16?g/kg?36.79?g/kg?41.75?g/kg?37.30?g/kg,resPectively.Different tyPes of mycotoxin adsorbent aPPlied in treatment 3⁶ which were NO.1 Absorbent?aluminosilicate?,NO.2 Absorbent?aluminosilicate?,NO.3 Absorbent?biodegradable?,NO.4 Absorbent?comPlex?.Body weight gain,average feed intake,feed body weight gain ratio in day 21,42 and61were record.On day 21 and 61of the exPeriment,twelve chickens were randomly chosen for blood collection form vein and then slaughtered for organs observation.The biochemical indices were measured in serum from the blood samPles.Results showed that:?1?There was no significant difference in Body weight gain,average feed intake or feed body weight gain ratio?P>0.05?.Here was no significant difference in the overall use of high AFB₁ diet and the comParison results with high AFB₁ only in the middle and late stage?P>0.05?.?2?In exPeriment 1,there was no significant difference in activities of SOD or APL as well as MDA and H₂O₂ level among treatments?P>0.05?on day 21.Activities of SOD in chickens ingested high AFB₁ diets were numerically lower than control.There was no significant difference in levels of MDA or H₂O₂ level among treatments?P>0.05?on day 61.Activities of SOD,GSH-PX and POD showed significant different?P<0.05?among treatment.Activity of SOD?GSH-PX from chicken intake diets contained 50 and 100?g/kg AFB₁was lower than other treatments.?3?In exPeriment 1,there was significant difference in ALB content among treatments?P<0.05?on day 21.Levels of ALB in high AFB₁ contaminated treatments were lower than control.There were no significant difference in AST activity or GLOB level on day21 and AST or levels of GLOB and ALB on day 61?4?The survival rate of chickens was imProved in high AFB₁ contained diet with mycotoxin adsorbents.?5?In exPeriment 2,there was no significant difference in activities of SOD,GSH-PXH or APL as well as MDA and H₂O₂ level among treatments?P>0.05?on day 21 and day 61.?6?In exPeriment 2,there was no significant difference in levels of ALB and GLOB or AST activity among treatments?P>0.05?on day 21 and day 61.?7?No histological difference was observed among treatments in liver.